Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFIOG_RS10385 Genome accession   NZ_CP170422
Coordinates   2070218..2070934 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain t7558     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2065218..2075934
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOG_RS10355 - 2065433..2066059 (+) 627 WP_000522384.1 nitroreductase family protein -
  ACFIOG_RS10360 - 2066420..2067205 (+) 786 WP_410537412.1 carbon-nitrogen family hydrolase -
  ACFIOG_RS10365 hld 2067805..2067885 (-) 81 WP_000046022.1 delta-hemolysin -
  ACFIOG_RS10370 - 2068175..2068738 (+) 564 WP_001105704.1 accessory gene regulator AgrB -
  ACFIOG_RS10375 agrD 2068742..2068882 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  ACFIOG_RS10380 agrC 2068907..2070199 (+) 1293 WP_000387801.1 quorum-sensing sensor histidine kinase AgrC -
  ACFIOG_RS10385 agrA 2070218..2070934 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  ACFIOG_RS10390 - 2071006..2071115 (+) 110 Protein_2010 hypothetical protein -
  ACFIOG_RS10395 - 2071303..2072262 (-) 960 WP_001253293.1 carbohydrate kinase family protein -
  ACFIOG_RS10400 - 2072259..2073743 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  ACFIOG_RS10405 - 2073892..2074842 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=1057121 ACFIOG_RS10385 WP_000688498.1 2070218..2070934(+) (agrA) [Staphylococcus aureus strain t7558]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1057121 ACFIOG_RS10385 WP_000688498.1 2070218..2070934(+) (agrA) [Staphylococcus aureus strain t7558]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment