Detailed information NTG1057119

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACFIOG_RS09655
• Genome accession: NZ_CP170422
• Coordinates: 1950100..1951143 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain t7558
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1945100..1956143

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFIOG_RS09625	-	1945522..1946778 (-)	1257	WP_072398252.1	aminopeptidase	-
ACFIOG_RS09630	-	1946781..1946981 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACFIOG_RS09635	-	1947128..1947592 (+)	465	WP_000567539.1	low molecular weight protein-tyrosine-phosphatase	-
ACFIOG_RS09640	-	1947599..1947874 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACFIOG_RS09645	-	1948152..1949369 (+)	1218	WP_000037084.1	YihY/virulence factor BrkB family protein	-
ACFIOG_RS09650	vraR	1949481..1950110 (-)	630	WP_000153532.1	two-component system response regulator VraR	Regulator
ACFIOG_RS09655	vraS	1950100..1951143 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACFIOG_RS09660	liaF	1951140..1951841 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACFIOG_RS09665	-	1951856..1952242 (-)	387	WP_001110179.1	hypothetical protein	-
ACFIOG_RS09670	map	1952459..1953217 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACFIOG_RS09675	-	1953689..1954675 (+)	987	WP_000999713.1	FUSC family protein	-
ACFIOG_RS09680	-	1955106..1955519 (-)	414	WP_025175030.1	hypothetical protein	-
ACFIOG_RS09685	-	1955548..1955658 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1057119 ACFIOG_RS09655 WP_001017131.1 1950100..1951143(-) (vraS) [Staphylococcus aureus strain t7558]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1057119 ACFIOG_RS09655 WP_001017131.1 1950100..1951143(-) (vraS) [Staphylococcus aureus strain t7558]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTGAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1