Detailed information NTG1057075

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACFIOC_RS09760
• Genome accession: NZ_CP170419
• Coordinates: 1961326..1962369 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain t062
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1956326..1967369

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFIOC_RS09730	-	1956747..1958003 (-)	1257	WP_001795108.1	aminopeptidase	-
ACFIOC_RS09735	-	1958006..1958206 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACFIOC_RS09740	-	1958353..1958817 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACFIOC_RS09745	-	1958824..1959099 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACFIOC_RS09750	-	1959377..1960594 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
ACFIOC_RS09755	vraR	1960707..1961336 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACFIOC_RS09760	vraS	1961326..1962369 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACFIOC_RS09765	liaF	1962366..1963067 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACFIOC_RS09770	-	1963082..1963468 (-)	387	WP_001110179.1	hypothetical protein	-
ACFIOC_RS09775	map	1963685..1964443 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACFIOC_RS09780	-	1964974..1965960 (+)	987	WP_000999717.1	FUSC family protein	-
ACFIOC_RS09785	-	1966391..1966804 (-)	414	WP_001557448.1	hypothetical protein	-
ACFIOC_RS09790	-	1966833..1966943 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1057075 ACFIOC_RS09760 WP_001017131.1 1961326..1962369(-) (vraS) [Staphylococcus aureus strain t062]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1057075 ACFIOC_RS09760 WP_001017131.1 1961326..1962369(-) (vraS) [Staphylococcus aureus strain t062]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1