Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFIOT_RS03490 Genome accession   NZ_CP170414
Coordinates   709892..710608 (-) Length   238 a.a.
NCBI ID   WP_054189591.1    Uniprot ID   -
Organism   Staphylococcus aureus strain t5047     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 704892..715608
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOT_RS03470 - 705976..706926 (+) 951 WP_410535747.1 LacI family DNA-binding transcriptional regulator -
  ACFIOT_RS03475 - 707075..708559 (+) 1485 WP_054189589.1 sucrose-6-phosphate hydrolase -
  ACFIOT_RS03480 - 708556..709515 (+) 960 WP_054189590.1 carbohydrate kinase family protein -
  ACFIOT_RS03485 - 709712..709820 (-) 109 Protein_682 hypothetical protein -
  ACFIOT_RS03490 agrA 709892..710608 (-) 717 WP_054189591.1 quorum-sensing response regulator AgrA Regulator
  ACFIOT_RS03495 agrC 710627..711919 (-) 1293 WP_054189592.1 quorum-sensing sensor histidine kinase AgrC -
  ACFIOT_RS03500 agrD 711944..712084 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACFIOT_RS03505 - 712081..712650 (-) 570 WP_054189593.1 accessory gene regulator AgrB -
  ACFIOT_RS03510 hld 712940..713020 (+) 81 WP_000046022.1 delta-hemolysin -
  ACFIOT_RS03515 - 713616..714401 (-) 786 WP_054189594.1 carbon-nitrogen family hydrolase -
  ACFIOT_RS03520 - 714722..715348 (-) 627 WP_054189595.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27904.92 Da        Isoelectric Point: 6.3001

>NTDB_id=1056962 ACFIOT_RS03490 WP_054189591.1 709892..710608(-) (agrA) [Staphylococcus aureus strain t5047]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDNRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1056962 ACFIOT_RS03490 WP_054189591.1 709892..710608(-) (agrA) [Staphylococcus aureus strain t5047]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACCGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCCGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATAATCGCTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment