Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFIOR_RS03565 Genome accession   NZ_CP170409
Coordinates   715689..716405 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain t359     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 710689..721405
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOR_RS03545 - 711781..712731 (+) 951 WP_000790324.1 LacI family DNA-binding transcriptional regulator -
  ACFIOR_RS03550 - 712880..714364 (+) 1485 WP_000141426.1 sucrose-6-phosphate hydrolase -
  ACFIOR_RS03555 - 714361..715320 (+) 960 WP_001253302.1 carbohydrate kinase family protein -
  ACFIOR_RS03560 - 715508..715617 (-) 110 Protein_697 hypothetical protein -
  ACFIOR_RS03565 agrA 715689..716405 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  ACFIOR_RS03570 agrC 716424..717716 (-) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  ACFIOR_RS03575 agrD 717741..717881 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACFIOR_RS03580 agrB 717878..718447 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  ACFIOR_RS03585 hld 718737..718817 (+) 81 WP_000046022.1 delta-hemolysin -
  ACFIOR_RS03590 - 719413..720198 (-) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  ACFIOR_RS03595 - 720559..721185 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=1056878 ACFIOR_RS03565 WP_000688498.1 715689..716405(-) (agrA) [Staphylococcus aureus strain t359]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1056878 ACFIOR_RS03565 WP_000688498.1 715689..716405(-) (agrA) [Staphylococcus aureus strain t359]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment