Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFIOO_RS10280 Genome accession   NZ_CP170406
Coordinates   2071395..2072111 (+) Length   238 a.a.
NCBI ID   WP_054189591.1    Uniprot ID   -
Organism   Staphylococcus aureus strain t21635     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2066395..2077111
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOO_RS10250 - 2066655..2067281 (+) 627 WP_054189595.1 nitroreductase family protein -
  ACFIOO_RS10255 - 2067602..2068387 (+) 786 WP_054189594.1 carbon-nitrogen family hydrolase -
  ACFIOO_RS10260 hld 2068983..2069063 (-) 81 WP_000046022.1 delta-hemolysin -
  ACFIOO_RS10265 - 2069353..2069922 (+) 570 WP_054189593.1 accessory gene regulator AgrB -
  ACFIOO_RS10270 agrD 2069919..2070059 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACFIOO_RS10275 agrC 2070084..2071376 (+) 1293 WP_054189592.1 quorum-sensing sensor histidine kinase AgrC -
  ACFIOO_RS10280 agrA 2071395..2072111 (+) 717 WP_054189591.1 quorum-sensing response regulator AgrA Regulator
  ACFIOO_RS10285 - 2072183..2072291 (+) 109 Protein_1987 hypothetical protein -
  ACFIOO_RS10290 - 2072488..2073447 (-) 960 WP_054189590.1 carbohydrate kinase family protein -
  ACFIOO_RS10295 - 2073444..2074928 (-) 1485 WP_054189589.1 sucrose-6-phosphate hydrolase -
  ACFIOO_RS10300 - 2075077..2076027 (-) 951 WP_054189588.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27904.92 Da        Isoelectric Point: 6.3001

>NTDB_id=1056867 ACFIOO_RS10280 WP_054189591.1 2071395..2072111(+) (agrA) [Staphylococcus aureus strain t21635]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDNRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1056867 ACFIOO_RS10280 WP_054189591.1 2071395..2072111(+) (agrA) [Staphylococcus aureus strain t21635]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACCGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCCGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATAATCGCTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment