Detailed information NTG1056798

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACFIOQ_RS04315
• Genome accession: NZ_CP170404
• Coordinates: 842311..843354 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain t7960
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 837311..848354

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFIOQ_RS04280	-	837813..837923 (+)	111	WP_001790257.1	hypothetical protein	-
ACFIOQ_RS04285	-	837952..838365 (+)	414	WP_025174475.1	hypothetical protein	-
ACFIOQ_RS04290	-	838554..839540 (-)	987	WP_000999713.1	FUSC family protein	-
ACFIOQ_RS04295	-	839713..840168 (+)	456	WP_142392776.1	hypothetical protein	-
ACFIOQ_RS04300	map	840237..840995 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACFIOQ_RS04305	-	841212..841598 (+)	387	WP_001110179.1	hypothetical protein	-
ACFIOQ_RS04310	liaF	841613..842314 (+)	702	WP_000149068.1	cell wall-active antibiotics response protein LiaF	-
ACFIOQ_RS04315	vraS	842311..843354 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACFIOQ_RS04320	vraR	843344..843973 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
ACFIOQ_RS04325	-	844086..845303 (-)	1218	WP_000037088.1	YihY/virulence factor BrkB family protein	-
ACFIOQ_RS04330	-	845581..845856 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
ACFIOQ_RS04335	-	845863..846327 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACFIOQ_RS04340	-	846474..846674 (+)	201	WP_000180462.1	DUF1128 family protein	-
ACFIOQ_RS04345	-	846677..847933 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1056798 ACFIOQ_RS04315 WP_001017131.1 842311..843354(+) (vraS) [Staphylococcus aureus strain t7960]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1056798 ACFIOQ_RS04315 WP_001017131.1 842311..843354(+) (vraS) [Staphylococcus aureus strain t7960]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATTTTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATT
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCGGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1