Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFIOQ_RS03515 Genome accession   NZ_CP170404
Coordinates   712920..713636 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain t7960     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 707920..718636
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOQ_RS03495 - 709015..709965 (+) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -
  ACFIOQ_RS03500 - 710114..711598 (+) 1485 WP_410532192.1 sucrose-6-phosphate hydrolase -
  ACFIOQ_RS03505 - 711595..712554 (+) 960 WP_001253302.1 carbohydrate kinase family protein -
  ACFIOQ_RS03510 - 712741..712848 (-) 108 WP_031927410.1 hypothetical protein -
  ACFIOQ_RS03515 agrA 712920..713636 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACFIOQ_RS03520 agrC 713655..714947 (-) 1293 WP_001807128.1 quorum-sensing sensor histidine kinase AgrC -
  ACFIOQ_RS03525 agrD 714972..715112 (-) 141 WP_001094303.1 cyclic lactone autoinducer peptide AgrD -
  ACFIOQ_RS03530 - 715114..715677 (-) 564 WP_001105716.1 accessory gene regulator AgrB -
  ACFIOQ_RS03535 hld 715968..716048 (+) 81 WP_000046023.1 delta-hemolysin -
  ACFIOQ_RS03540 - 716646..717431 (-) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  ACFIOQ_RS03545 - 717792..718418 (-) 627 WP_000522380.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1056797 ACFIOQ_RS03515 WP_000688492.1 712920..713636(-) (agrA) [Staphylococcus aureus strain t7960]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1056797 ACFIOQ_RS03515 WP_000688492.1 712920..713636(-) (agrA) [Staphylococcus aureus strain t7960]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCAAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCAGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment