Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFIOF_RS03590 Genome accession   NZ_CP170397
Coordinates   717815..718531 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain t3841     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 712815..723531
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOF_RS03570 - 713907..714857 (+) 951 WP_000790332.1 LacI family DNA-binding transcriptional regulator -
  ACFIOF_RS03575 - 715006..716490 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  ACFIOF_RS03580 - 716487..717446 (+) 960 WP_001253314.1 carbohydrate kinase family protein -
  ACFIOF_RS03585 - 717634..717743 (-) 110 Protein_702 hypothetical protein -
  ACFIOF_RS03590 agrA 717815..718531 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACFIOF_RS03595 agrC 718550..719842 (-) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  ACFIOF_RS03600 agrD 719867..720007 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACFIOF_RS03605 agrB 720004..720573 (-) 570 WP_410540641.1 accessory gene regulator AgrB -
  ACFIOF_RS03610 hld 720863..720943 (+) 81 WP_000046022.1 delta-hemolysin -
  ACFIOF_RS03615 - 721540..722325 (-) 786 WP_000867949.1 carbon-nitrogen family hydrolase -
  ACFIOF_RS03620 - 722686..723312 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1056669 ACFIOF_RS03590 WP_000688492.1 717815..718531(-) (agrA) [Staphylococcus aureus strain t3841]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1056669 ACFIOF_RS03590 WP_000688492.1 717815..718531(-) (agrA) [Staphylococcus aureus strain t3841]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment