Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFIOH_RS03495 Genome accession   NZ_CP170389
Coordinates   712083..712799 (-) Length   238 a.a.
NCBI ID   WP_054189591.1    Uniprot ID   -
Organism   Staphylococcus aureus strain t14667     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 707083..717799
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOH_RS03475 - 708167..709117 (+) 951 WP_054189588.1 LacI family DNA-binding transcriptional regulator -
  ACFIOH_RS03480 - 709266..710750 (+) 1485 WP_054189589.1 sucrose-6-phosphate hydrolase -
  ACFIOH_RS03485 - 710747..711706 (+) 960 WP_054189590.1 carbohydrate kinase family protein -
  ACFIOH_RS03490 - 711903..712011 (-) 109 Protein_683 hypothetical protein -
  ACFIOH_RS03495 agrA 712083..712799 (-) 717 WP_054189591.1 quorum-sensing response regulator AgrA Regulator
  ACFIOH_RS03500 agrC 712818..714110 (-) 1293 WP_054189592.1 quorum-sensing sensor histidine kinase AgrC -
  ACFIOH_RS03505 agrD 714135..714275 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACFIOH_RS03510 - 714272..714841 (-) 570 WP_054189593.1 accessory gene regulator AgrB -
  ACFIOH_RS03515 hld 715131..715211 (+) 81 WP_000046022.1 delta-hemolysin -
  ACFIOH_RS03520 - 715807..716592 (-) 786 WP_054189594.1 carbon-nitrogen family hydrolase -
  ACFIOH_RS03525 - 716913..717539 (-) 627 WP_054189595.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27904.92 Da        Isoelectric Point: 6.3001

>NTDB_id=1056548 ACFIOH_RS03495 WP_054189591.1 712083..712799(-) (agrA) [Staphylococcus aureus strain t14667]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDNRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1056548 ACFIOH_RS03495 WP_054189591.1 712083..712799(-) (agrA) [Staphylococcus aureus strain t14667]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACCGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCCGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATAATCGCTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment