Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACFBUK_RS05780 Genome accession   NZ_CP170331
Coordinates   1115122..1115778 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain GDMCC 820630     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1110122..1120778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFBUK_RS05750 (ACFBUK_05750) oppF 1110652..1111569 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ACFBUK_RS05755 (ACFBUK_05755) - 1111676..1112863 (+) 1188 WP_079891125.1 putative glycoside hydrolase -
  ACFBUK_RS05760 (ACFBUK_05760) - 1112981..1113559 (+) 579 WP_032874457.1 GNAT family N-acetyltransferase -
  ACFBUK_RS05765 (ACFBUK_05765) spx 1113738..1114133 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  ACFBUK_RS05770 (ACFBUK_05770) - 1114190..1114846 (-) 657 WP_032874459.1 TerC family protein -
  ACFBUK_RS05775 (ACFBUK_05775) - 1115029..1115139 (+) 111 Protein_1075 adaptor protein MecA -
  ACFBUK_RS05780 (ACFBUK_05780) mecA 1115122..1115778 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  ACFBUK_RS05785 (ACFBUK_05785) - 1115929..1117089 (+) 1161 WP_032874460.1 competence protein CoiA family protein -
  ACFBUK_RS05790 (ACFBUK_05790) pepF 1117317..1119146 (+) 1830 WP_087920792.1 oligoendopeptidase F Regulator
  ACFBUK_RS05795 (ACFBUK_05795) - 1119184..1119351 (-) 168 WP_032874462.1 hypothetical protein -
  ACFBUK_RS05800 (ACFBUK_05800) spxH 1119637..1120539 (-) 903 WP_032874464.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=1056130 ACFBUK_RS05780 WP_003155032.1 1115122..1115778(+) (mecA) [Bacillus velezensis strain GDMCC 820630]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1056130 ACFBUK_RS05780 WP_003155032.1 1115122..1115778(+) (mecA) [Bacillus velezensis strain GDMCC 820630]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAGA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment