Detailed information NTG1056063

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACFDA3_RS04430
• Genome accession: NZ_CP170251
• Coordinates: 961844..962890 (+)
• Length: 348 a.a.
• NCBI ID: WP_002490308.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain PS08
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 956844..967890

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFDA3_RS04405 (ACFDA3_04400)	-	957984..958520 (+)	537	WP_002447446.1	hypothetical protein	-
ACFDA3_RS04410 (ACFDA3_04405)	-	958672..959658 (-)	987	WP_002447445.1	aromatic acid exporter family protein	-
ACFDA3_RS04415 (ACFDA3_04410)	map	959832..960587 (+)	756	WP_002447444.1	type I methionyl aminopeptidase	-
ACFDA3_RS04420 (ACFDA3_04415)	-	960745..961131 (+)	387	WP_381410530.1	hypothetical protein	-
ACFDA3_RS04425 (ACFDA3_04420)	liaF	961146..961847 (+)	702	WP_002447442.1	cell wall-active antibiotics response protein LiaF	-
ACFDA3_RS04430 (ACFDA3_04425)	vraS	961844..962890 (+)	1047	WP_002490308.1	sensor histidine kinase	Regulator
ACFDA3_RS04435 (ACFDA3_04430)	vraR	962880..963509 (+)	630	WP_002473914.1	two-component system response regulator VraR	Regulator
ACFDA3_RS04440 (ACFDA3_04435)	-	963566..964744 (-)	1179	WP_002487362.1	YihY/virulence factor BrkB family protein	-
ACFDA3_RS04445 (ACFDA3_04440)	-	965150..965434 (-)	285	WP_002447438.1	YtxH domain-containing protein	-
ACFDA3_RS04450 (ACFDA3_04445)	-	965442..965906 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
ACFDA3_RS04455 (ACFDA3_04450)	-	966048..966263 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
ACFDA3_RS04460 (ACFDA3_04455)	-	966265..967506 (+)	1242	WP_381410531.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40100.51 Da
• Isoelectric Point: 5.8512

>NTDB_id=1056063 ACFDA3_RS04430 WP_002490308.1 961844..962890(+) (vraS) [Staphylococcus epidermidis strain PS08]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVFLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=1056063 ACFDA3_RS04430 WP_002490308.1 961844..962890(+) (vraS) [Staphylococcus epidermidis strain PS08]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAAGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATAGTTTTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCC
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAGAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCAAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCTGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.733	98.851	0.917