Detailed information NTG1056031

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACFDBA_RS04650
• Genome accession: NZ_CP170250
• Coordinates: 969398..970444 (+)
• Length: 348 a.a.
• NCBI ID: WP_002447441.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain PS21
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 964398..975444

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFDBA_RS04625 (ACFDBA_04620)	-	965538..966074 (+)	537	WP_002447446.1	hypothetical protein	-
ACFDBA_RS04630 (ACFDBA_04625)	-	966226..967212 (-)	987	WP_002447445.1	aromatic acid exporter family protein	-
ACFDBA_RS04635 (ACFDBA_04630)	map	967386..968141 (+)	756	WP_002447444.1	type I methionyl aminopeptidase	-
ACFDBA_RS04640 (ACFDBA_04635)	-	968299..968685 (+)	387	WP_002491498.1	hypothetical protein	-
ACFDBA_RS04645 (ACFDBA_04640)	liaF	968700..969401 (+)	702	WP_381414494.1	cell wall-active antibiotics response protein LiaF	-
ACFDBA_RS04650 (ACFDBA_04645)	vraS	969398..970444 (+)	1047	WP_002447441.1	sensor histidine kinase	Regulator
ACFDBA_RS04655 (ACFDBA_04650)	vraR	970434..971063 (+)	630	WP_002473914.1	two-component system response regulator VraR	Regulator
ACFDBA_RS04660 (ACFDBA_04655)	-	971120..972298 (-)	1179	WP_381414496.1	YihY/virulence factor BrkB family protein	-
ACFDBA_RS04665 (ACFDBA_04660)	-	972704..972988 (-)	285	WP_002447438.1	YtxH domain-containing protein	-
ACFDBA_RS04670 (ACFDBA_04665)	-	972996..973460 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
ACFDBA_RS04675 (ACFDBA_04670)	-	973602..973817 (+)	216	WP_381414498.1	DUF1128 domain-containing protein	-
ACFDBA_RS04680 (ACFDBA_04675)	-	973819..975060 (+)	1242	WP_002458545.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40114.53 Da
• Isoelectric Point: 5.8512

>NTDB_id=1056031 ACFDBA_RS04650 WP_002447441.1 969398..970444(+) (vraS) [Staphylococcus epidermidis strain PS21]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVFLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVLHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=1056031 ACFDBA_RS04650 WP_002447441.1 969398..970444(+) (vraS) [Staphylococcus epidermidis strain PS21]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAAGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATAGTTTTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCC
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAGAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAGCGACTTGCTAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCAGCAATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGGGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTTTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.442	98.851	0.914