Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   ACLV65_RS03090 Genome accession   NZ_OZ217342
Coordinates   593463..594140 (+) Length   225 a.a.
NCBI ID   WP_411864493.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis B22     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 588463..599140
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV65_RS03060 (SMIB22_05950) dtd 588999..589442 (+) 444 WP_301351154.1 D-aminoacyl-tRNA deacylase -
  ACLV65_RS03065 (SMIB22_05960) - 589481..589894 (-) 414 WP_411864489.1 hypothetical protein -
  ACLV65_RS03070 (SMIB22_05970) - 590060..590710 (-) 651 WP_411864490.1 metal-dependent transcriptional regulator -
  ACLV65_RS03075 (SMIB22_05980) - 590821..591663 (+) 843 WP_411864491.1 metallophosphoesterase family protein -
  ACLV65_RS03080 (SMIB22_05990) - 591739..592176 (+) 438 WP_001166788.1 Rrf2 family transcriptional regulator -
  ACLV65_RS03085 (SMIB22_06000) - 592234..593307 (-) 1074 WP_411864492.1 DUF2974 domain-containing protein -
  ACLV65_RS03090 (SMIB22_06010) braR 593463..594140 (+) 678 WP_411864493.1 response regulator transcription factor Regulator
  ACLV65_RS03095 (SMIB22_06020) - 594133..595107 (+) 975 WP_411864494.1 sensor histidine kinase -
  ACLV65_RS03100 (SMIB22_06030) thrS 595154..597097 (-) 1944 WP_411864495.1 threonine--tRNA ligase -
  ACLV65_RS03105 (SMIB22_06040) - 597151..597474 (-) 324 WP_061439696.1 hypothetical protein -
  ACLV65_RS03110 (SMIB22_06060) - 597732..598105 (-) 374 Protein_560 hypothetical protein -
  ACLV65_RS03115 (SMIB22_06070) rpsO 598310..598579 (+) 270 WP_001018251.1 30S ribosomal protein S15 -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25946.06 Da        Isoelectric Point: 5.1362

>NTDB_id=1055852 ACLV65_RS03090 WP_411864493.1 593463..594140(+) (braR) [Streptococcus mitis isolate S. mitis B22]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSESHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESFLEYAGVILNTKSMDVHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=1055852 ACLV65_RS03090 WP_411864493.1 593463..594140(+) (braR) [Streptococcus mitis isolate S. mitis B22]
ATGCACAAGATTTTATTAGTAGAAGATGATCAGGTTATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTTCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTTTTTGTCCAGTCGGAATCTCATCTGGTCCTCATGGATATTG
GCTTGCCCTTGTTTAATGGCTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTGCCGATTATGTTTCTGTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCCAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGACGAGAGTTTTCTGGAATATGCTGGTG
TGATTCTCAATACCAAATCCATGGATGTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGAGTTTTGTTTGAGCATGCGGGCAATATCGTAGCGCGTGATGACCTGATGCGGGAACTTTGGAATAGTGACTTTTTCAT
TGATGACAATACCCTATCTGTTAATGTAGCTCGATTGCGTAAAAAGTTGGAAGAGCAGGGCTTGGTAGGATTTATCGAGA
CCAAGAAAGGGATAGGGTACGGACTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476

Multiple sequence alignment