Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFDHT_RS04950 Genome accession   NZ_CP170227
Coordinates   1046543..1047265 (-) Length   240 a.a.
NCBI ID   WP_039644708.1    Uniprot ID   -
Organism   Staphylococcus hyicus strain SC368     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1041543..1052265
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFDHT_RS04930 (ACFDHT_04925) - 1042496..1043131 (+) 636 WP_039644703.1 redox-sensing transcriptional repressor Rex -
  ACFDHT_RS04935 (ACFDHT_04930) - 1043311..1044393 (+) 1083 WP_119635847.1 YeeE/YedE family protein -
  ACFDHT_RS04940 (ACFDHT_04935) - 1044418..1044642 (+) 225 WP_039644706.1 sulfurtransferase TusA family protein -
  ACFDHT_RS04945 (ACFDHT_04940) - 1044981..1046480 (+) 1500 WP_119635848.1 sucrose-6-phosphate hydrolase -
  ACFDHT_RS04950 (ACFDHT_04945) agrA 1046543..1047265 (-) 723 WP_039644708.1 quorum-sensing response regulator AgrA Regulator
  ACFDHT_RS04955 (ACFDHT_04950) agrC 1047279..1048577 (-) 1299 WP_107633493.1 quorum-sensing sensor histidine kinase AgrC -
  ACFDHT_RS04960 (ACFDHT_04955) agrD 1048607..1048741 (-) 135 WP_107633492.1 cyclic lactone autoinducer peptide AgrD -
  ACFDHT_RS04965 (ACFDHT_04960) - 1048744..1049307 (-) 564 WP_257054490.1 accessory gene regulator AgrB -
  ACFDHT_RS04970 (ACFDHT_04965) - 1049957..1050754 (-) 798 WP_039644715.1 carbon-nitrogen family hydrolase -
  ACFDHT_RS04975 (ACFDHT_04970) - 1050920..1051969 (+) 1050 WP_305850354.1 hypothetical protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28228.36 Da        Isoelectric Point: 5.4121

>NTDB_id=1055707 ACFDHT_RS04950 WP_039644708.1 1046543..1047265(-) (agrA) [Staphylococcus hyicus strain SC368]
MKILICEDDPKQRERMESIIQNYIMIEEKPMEIEISTSDPYALLEASKNMTDIGCYFLDIQLESDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKLAAMDFIFKDDIDELRTRIIDCLETALKRLDLLTKDNTVETMELKQGSNSVYVNYDDVM
FFESSPKSHRLIAHLDNRQIEFYGNLRELAQIDSRFFRCHNSFVLNRHNISHVDAKERIVYFKNDEFCYVSVRNIKKIKK

Nucleotide


Download         Length: 723 bp        

>NTDB_id=1055707 ACFDHT_RS04950 WP_039644708.1 1046543..1047265(-) (agrA) [Staphylococcus hyicus strain SC368]
TTGAAGATATTAATTTGTGAGGATGACCCTAAACAAAGAGAGCGAATGGAATCCATCATTCAAAATTATATTATGATTGA
AGAAAAGCCCATGGAAATTGAAATTTCTACAAGTGACCCATACGCGTTACTTGAGGCTTCAAAAAACATGACCGATATTG
GGTGTTACTTTTTAGATATCCAATTAGAATCTGATATTAATGGCATTAAGCTTGGCAGTGAAATTAGAAAACATGATCCC
GTAGGTAATATTATTTTTGTGACAAGCCATAGTGAATTAACGTATTTGACATTCGTTTATAAACTTGCTGCTATGGATTT
TATATTCAAAGACGATATTGATGAATTACGAACGCGCATTATTGATTGTCTTGAAACTGCGCTCAAACGGTTGGATTTAC
TTACTAAAGATAACACTGTAGAAACAATGGAATTAAAACAAGGCAGTAATTCTGTATATGTCAACTATGATGATGTCATG
TTTTTTGAATCTTCACCTAAGTCACATCGACTCATAGCTCACTTAGATAATCGACAAATTGAGTTTTATGGTAATTTAAG
GGAACTTGCACAAATTGATAGTCGCTTTTTTAGATGCCATAACAGTTTTGTTTTAAATCGTCATAACATCTCTCATGTTG
ATGCTAAAGAGCGTATTGTTTATTTTAAAAATGATGAGTTTTGCTATGTGTCAGTTAGAAATATAAAAAAAATCAAGAAA
TAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

81.933

99.167

0.813

Multiple sequence alignment