Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   ACLV7Q_RS00870 Genome accession   NZ_OZ217341
Coordinates   168367..170901 (+) Length   844 a.a.
NCBI ID   WP_218757572.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis C22     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 163367..175901
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Q_RS00850 (SMIC22_01620) - 164086..165102 (-) 1017 WP_004258896.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  ACLV7Q_RS00855 (SMIC22_01630) - 165271..165516 (-) 246 WP_173219891.1 MarR family transcriptional regulator -
  ACLV7Q_RS00860 (SMIC22_01640) argS 166044..167735 (-) 1692 WP_218757571.1 arginine--tRNA ligase -
  ACLV7Q_RS00865 (SMIC22_01650) argR 167870..168316 (+) 447 WP_001231476.1 arginine repressor -
  ACLV7Q_RS00870 (SMIC22_01670) hexA 168367..170901 (+) 2535 WP_218757572.1 DNA mismatch repair protein MutS Machinery gene
  ACLV7Q_RS00875 (SMIC22_01680) patA 171047..172753 (+) 1707 WP_218757573.1 multidrug efflux ABC transporter subunit PatA -
  ACLV7Q_RS00880 (SMIC22_01690) rcrQ 172755..174521 (+) 1767 WP_218757574.1 multidrug efflux ABC transporter subunit PatB Regulator
  ACLV7Q_RS00885 (SMIC22_01700) - 174659..175348 (+) 690 WP_218757575.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -

Sequence

Protein


Download         Length: 844 a.a.        Molecular weight: 94862.23 Da        Isoelectric Point: 4.8366

>NTDB_id=1055693 ACLV7Q_RS00870 WP_218757572.1 168367..170901(+) (hexA) [Streptococcus mitis isolate S. mitis C22]
MATEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLI
EQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKEGFEDLHLLDSRLASVEQAASSKLLQYVHRTQMRELNHLKP
VIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPMIDKERIIQRQEVVQVFLDHFF
ERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRGILEGMEQSALAYLIEQLDGIPELESLISAAIAP
EAPHVITEGGIIRTGFDETLDKYRRVLREGTGWIAEIEAKERENSGISTLKIDYNKKDGYYFHVTNSQLGNVPAHFFRKA
TLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVSKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFG
DDSRIDIQKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAIMAQMGSYVPAESARLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDELGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHEL
TSLESSLEHLVNVHVATLEQDGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGPESPDPMKQTSA
VTEQISLFDTPEEHPILEELAKLDVYNMTPMQAMNVLVELKQKL

Nucleotide


Download         Length: 2535 bp        

>NTDB_id=1055693 ACLV7Q_RS00870 WP_218757572.1 168367..170901(+) (hexA) [Streptococcus mitis isolate S. mitis C22]
ATGGCGACAGAAAAGCTATCACCCGGCATGCAACAGTATGTGGATATTAAAAAGCAATATCCAGATGCTTTTTTGCTCTT
TCGAATGGGTGATTTTTATGAATTATTTTATGAGGATGCAGTCAATGCTGCGCAGATTCTGGAAATTTCCTTAACGAGTC
GCAACAAGAATGCCGACAATCCGATTCCTATGGCGGGTGTTCCCTATCATTCTGCCCAACAGTATATTGATGTCTTGATT
GAGCAGGGTTATAAGGTGGCTATCGCAGAGCAGATGGAAGATCCTAAACAAGCAGTTGGAGTTGTGAAACGAGAGGTTGT
TCAGGTCATTACGCCAGGGACAGTGGTCGATAGCAGTAAGCCGGACAGTCAGAACAACTTCTTGGTTGCCATAGACCGCG
AAGGCAATCAATTTGGCCTAGCTTATATGGACCTGGTGACAGGGGACTTTTATGTGACAGGTCTTTTGGATTTCACGCTG
GTTTGTGGGGAAATCCGTAACCTCAAGGCTCGAGAAGTGGTGCTGGGTTATGACTTGTCTGAGGAAGAAGAACAAATTCT
TAGTCGTCAGATGAATCTGGTGCTTTCCTATGAAAAAGAAGGCTTTGAAGACCTTCATTTACTGGATTCACGATTGGCAT
CTGTGGAGCAAGCGGCATCCAGTAAGTTACTCCAGTATGTTCATCGGACTCAGATGAGGGAATTGAACCACCTCAAACCT
GTTATCCGCTACGAAATTAAGGATTTCTTGCAGATGGATTATGCGACCAAGGCTAGTCTGGATTTGGTTGAGAATGCCCG
TTCAGGCAAGAAGCAAGGCAGTCTTTTCTGGCTTTTGGATGAAACCAAAACAGCCATGGGTATGCGTCTCTTGCGTTCTT
GGATTCATCGTCCCATGATTGATAAGGAACGAATTATCCAACGTCAGGAAGTGGTGCAGGTCTTTCTCGACCATTTCTTT
GAGCGCAGTGATTTGACAGACAGTCTCAAGGGTGTTTATGACATTGAGCGCTTGGCTAGTCGGGTTTCTTTTGGTAAAAC
CAATCCCAAGGATCTCTTGCAGTTGGCGACTACCTTGTCTAGTGTGCCACGGATTCGTGGGATTTTAGAAGGAATGGAGC
AATCTGCTCTAGCCTATCTCATTGAACAACTGGATGGAATCCCTGAGTTGGAGAGTTTGATTAGCGCAGCGATTGCTCCT
GAAGCTCCTCATGTGATTACAGAAGGTGGTATTATCCGAACTGGATTTGATGAGACTTTAGACAAGTACCGTCGCGTTCT
CAGAGAAGGGACTGGCTGGATTGCTGAGATTGAGGCCAAGGAGAGAGAAAACTCTGGTATCAGCACGCTTAAGATTGACT
ACAATAAAAAGGATGGCTACTATTTCCATGTGACCAATTCTCAACTGGGAAATGTGCCTGCTCACTTTTTCCGCAAGGCA
ACGCTGAAAAACTCAGAACGTTTTGGAACCGAAGAATTAGCCCGTATCGAGGGCGATATGCTGGAGGCGCGTGAGAAGTC
AGCTAACCTAGAGTACGAAATTTTTATGCGCATTCGTGAAGAGGTCAGCAAGTACATCCAACGTTTACAAGCTCTAGCCC
AAGGAATTGCGACAGTTGATGTCCTGCAAAGTCTCGCAGTTGTTGCTGAAACCCAGCATTTGATTCGACCTGAATTCGGA
GATGATTCGCGAATTGATATCCAGAAAGGGCGCCATGCTGTCGTTGAAAAGGTCATGGGGGCTCAGACCTATATTCCCAA
TACGATTCAGATGGCAGAAGATACCAGTATTCAACTGATTACAGGGCCCAACATGAGTGGGAAGTCAACCTATATGCGTC
AGTTAGCCATGACGGCGATAATGGCCCAGATGGGTTCCTATGTACCGGCAGAAAGCGCCCGTTTACCGATTTTTGATGCG
ATCTTTACCCGTATCGGAGCAGCCGATGACTTGGTTTCGGGTCAGTCAACCTTTATGGTGGAGATGATGGAGGCCAATAA
TGCCATTTCGCATGCCACCAAAAATTCCTTGATTCTCTTTGATGAGTTAGGTCGTGGAACTGCAACTTACGACGGTATGG
CTCTTGCTCAGTCCATCATCGAATACATTCATGAACATATCGGAGCCAAGACCCTCTTTGCGACCCACTACCATGAGTTG
ACTAGCCTAGAGTCTAGCTTGGAACATTTAGTCAATGTCCATGTGGCAACCTTGGAGCAGGATGGACAGGTCACTTTCCT
TCATAAGATTGAACCAGGCCCAGCTGACAAATCCTACGGTATCCATGTAGCCAAGATTGCTGGCTTGCCAGCAGACCTTT
TAGCAAGGGCGGATAAGATTTTGACTCAGTTAGAGAATCAGGGCCCAGAAAGCCCAGATCCTATGAAACAAACAAGTGCC
GTCACTGAACAGATTTCTCTCTTTGATACACCTGAAGAACATCCTATCCTAGAAGAATTAGCTAAACTGGATGTTTACAA
TATGACACCTATGCAGGCTATGAATGTCTTGGTCGAGTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

MutS domain I (MutS_I)

(8-118)

MutS domain II (MutS_II)

(126-239)

MutS domain V (MutS_V)

(599-785)

MutS family domain IV (MutS_IV)

(415-505)

MutS domain III (MutS_III)

(256-546)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

96.327

100

0.963
  mutS Pseudomonas stutzeri strain ATCC 17587

36.183

100

0.366

Multiple sequence alignment