Detailed information NTG1055673

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: ACLV7H_RS09240
• Genome accession: NZ_OZ217340
• Coordinates: 1801471..1804008 (-)
• Length: 845 a.a.
• NCBI ID: WP_411866988.1
• Uniprot ID: -
• Organism: Streptococcus oralis isolate S. oralis A22
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1796471..1809008

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7H_RS09215 (SORA22_18580)	ruvA	1796973..1797566 (-)	594	WP_000273410.1	Holliday junction branch migration protein RuvA	Machinery gene
ACLV7H_RS09220 (SORA22_18590)	-	1797726..1798223 (+)	498	WP_227232030.1	helix-turn-helix domain-containing protein	-
ACLV7H_RS09225 (SORA22_18600)	hexB	1798376..1800325 (-)	1950	WP_227232029.1	DNA mismatch repair endonuclease MutL	Machinery gene
ACLV7H_RS09230 (SORA22_18610)	-	1800535..1800975 (+)	441	WP_411866986.1	LytTR family DNA-binding domain-containing protein	-
ACLV7H_RS09235 (SORA22_18620)	-	1800972..1801430 (+)	459	WP_411866987.1	DUF3021 domain-containing protein	-
ACLV7H_RS09240 (SORA22_18630)	hexA	1801471..1804008 (-)	2538	WP_411866988.1	DNA mismatch repair protein MutS	Machinery gene
ACLV7H_RS09245 (SORA22_18650)	argR	1804059..1804505 (-)	447	WP_001231483.1	arginine repressor	-
ACLV7H_RS09250 (SORA22_18660)	argS	1804660..1806351 (+)	1692	WP_411866989.1	arginine--tRNA ligase	-
ACLV7H_RS09255 (SORA22_18670)	-	1806840..1807085 (+)	246	WP_411866990.1	MarR family transcriptional regulator	-
ACLV7H_RS09260 (SORA22_18680)	-	1807284..1808546 (+)	1263	WP_411866991.1	NRAMP family divalent metal transporter	-

Sequence

Protein

• Length: 845 a.a.
• Molecular weight: 94758.18 Da
• Isoelectric Point: 4.8868

>NTDB_id=1055673 ACLV7H_RS09240 WP_411866988.1 1801471..1804008(-) (hexA) [Streptococcus oralis isolate S. oralis A22]
MATEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAINAAQILEISLTSRNKNAENPIPMAGVPYHSAQQYIDVLI
EQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDRDGNQFGLAYMDLVTGDFYVTGLLDFTL
VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKEGFEDIHLLDPRLAAVEQAAASKLLQYVHRTQMRELNHLKP
VIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFF
ERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIEQLDAIPELESLISAAIAP
EAPHVITEGGIIRTGFDETLDKYRRVLREGTSWIAEIEAKERENSGISTLKIDYNKKDGYYFHVTNSQLGNVPAHFFRKA
TLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVSKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFG
DDSQIDIQKGRHAVVEKVMGAQTYIPNSIQMSEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQLGSYVPAESAYLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANNAISHATKDSLILFDELGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHEL
TSLESSLKHLVNVHVATLEQDGQVTFLHKIEPGPADKSYGIHVAKIAGLPGELLARADKILTQLESQGGESPAPMRQTSA
VANEQISLFDTPAEHPILAELAKLDVYNMTPMQAMNVLVEFKQKL

Nucleotide

• Length: 2538 bp

>NTDB_id=1055673 ACLV7H_RS09240 WP_411866988.1 1801471..1804008(-) (hexA) [Streptococcus oralis isolate S. oralis A22]
ATGGCAACAGAAAAGCTATCACCCGGCATGCAACAGTATGTGGATATTAAAAAACAATACCCAGATGCTTTTTTGCTTTT
TCGAATGGGTGATTTTTACGAGTTGTTCTATGAAGATGCAATTAATGCAGCACAAATTTTAGAAATTTCCTTAACAAGTC
GGAATAAAAATGCAGAAAATCCGATACCCATGGCAGGTGTCCCCTATCATTCTGCCCAGCAGTATATCGACGTATTGATC
GAGCAGGGCTATAAGGTGGCCATAGCCGAGCAGATGGAAGATCCCAAACAAGCAGTGGGGGTTGTCAAGCGAGAGGTGGT
TCAGGTCATCACACCTGGTACAGTAGTCGATAGCAGTAAGCCCGATAGTCAGAATAATTTCTTGGTTGCCTTAGATCGTG
ATGGCAATCAATTTGGCCTGGCTTATATGGATCTAGTGACAGGTGATTTTTATGTGACAGGTTTATTGGATTTTACTCTC
GTTTGTGGGGAAATTCGTAACCTCAAGGCTCGAGAAGTGGTGCTGGGTTATGACTTGTCTGAGGAAGAAGAACAAATCCT
CAGTCGTCAGATGAATCTTGTGCTTTCCTATGAGAAGGAAGGCTTTGAGGATATTCATTTACTGGATCCACGCCTGGCAG
CTGTGGAGCAAGCGGCAGCTAGTAAGCTTCTACAGTATGTTCACCGGACCCAGATGCGGGAATTGAACCATCTCAAACCA
GTTATCCGCTATGAAATCAAAGATTTCTTACAGATGGATTATGCGACCAAGGCCAGTCTGGATTTGGTTGAAAATGCCCG
TTCAGGCAAGAAGCAAGGGAGTCTTTTTTGGCTTTTGGACGAAACCAAAACGGCTATGGGTATGCGGCTCTTACGGTCTT
GGATTCATCGTCCCTTGATTGATAAGGAACGAATTGTCCAACGTCAAGAGGTGGTGCAGGTCTTTCTTGACCACTTCTTT
GAGCGCAGTGATTTAACGGACAGTCTCAAGGGTGTTTATGATATCGAACGTTTGGCTAGTCGGGTTTCTTTTGGCAAGAC
CAATCCCAAGGATCTCTTGCAATTGGCGACCACCTTATCCAGTGTACCACGGATTCGTGCGATTTTAGAAGGCATGGAGC
AACCTGCCCTGGCCTATCTTATCGAACAGTTAGATGCCATCCCTGAGTTGGAGAGCTTGATTAGTGCTGCCATTGCTCCT
GAAGCTCCTCACGTGATTACGGAAGGTGGCATTATCCGTACGGGATTTGATGAGACCTTGGATAAATACCGTCGTGTTCT
CAGAGAAGGGACTAGCTGGATTGCTGAGATTGAGGCTAAGGAGAGAGAAAACTCTGGCATCAGCACTCTCAAGATTGACT
ACAATAAAAAGGACGGCTACTATTTCCATGTGACTAATTCGCAACTGGGAAATGTGCCAGCCCACTTTTTCCGCAAGGCA
ACGCTGAAAAACTCAGAACGCTTTGGTACCGAAGAATTAGCCCGTATCGAGGGAGATATGCTGGAGGCGCGTGAGAAGTC
AGCCAACCTAGAATATGAAATCTTTATGCGTATCCGTGAAGAGGTCAGCAAGTACATTCAGCGTTTGCAGGCTTTAGCCC
AAGGAATTGCGACGGTTGATGTCTTGCAAAGTCTCGCAGTTGTGGCTGAAACACAGCATTTGATCCGACCTGAGTTTGGG
GATGATTCACAAATCGATATCCAAAAGGGACGCCATGCTGTCGTCGAAAAGGTCATGGGAGCTCAGACCTACATTCCAAA
CAGTATCCAGATGTCAGAAGACACCAGTATTCAGCTAATTACAGGGCCCAACATGAGTGGGAAGTCTACTTATATGCGCC
AGTTAGCTATGACGGCGGTTATGGCCCAGCTAGGCTCGTATGTGCCGGCTGAGAGCGCCTACTTGCCTATCTTCGATGCT
ATCTTTACTCGCATCGGAGCGGCAGATGACTTGGTTTCAGGTCAATCAACCTTTATGGTGGAGATGATGGAGGCTAACAA
TGCCATTTCGCATGCGACCAAGGACTCCTTGATTCTCTTTGATGAGTTAGGACGGGGAACTGCGACTTATGACGGGATGG
CTCTTGCCCAGTCCATCATCGAATATATTCATGAACATATCGGAGCCAAAACTCTCTTTGCGACCCACTACCATGAGTTG
ACTAGTCTGGAGTCCAGCTTAAAACACTTGGTCAATGTCCATGTGGCGACCTTGGAGCAGGATGGGCAGGTTACCTTCCT
TCATAAGATCGAACCAGGACCAGCTGACAAATCCTACGGTATCCATGTGGCTAAGATTGCTGGCTTGCCAGGAGAACTTT
TAGCAAGGGCGGATAAGATATTGACTCAACTGGAGAGTCAAGGGGGAGAAAGTCCTGCTCCGATGAGGCAAACTAGCGCC
GTAGCCAATGAACAAATTTCATTATTTGACACGCCAGCAGAACATCCTATCCTAGCAGAATTAGCTAAACTGGATGTGTA
CAATATGACACCTATGCAGGCTATGAATGTCTTAGTTGAGTTCAAACAAAAATTATAA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	95.74	100	0.957
mutS	Pseudomonas stutzeri strain ATCC 17587	36.799	100	0.373