Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   DI45_RS05195 Genome accession   NZ_CP007560
Coordinates   998436..998912 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain NGAS743     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 993436..1003912
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DI45_RS05180 (DI45_05395) fbp54 994249..995901 (+) 1653 WP_047235325.1 Rqc2 family fibronectin-binding protein Fbp54 -
  DI45_RS05185 (DI45_05400) - 995960..997207 (-) 1248 WP_047235326.1 tetratricopeptide repeat protein -
  DI45_RS05190 (DI45_05405) - 997197..998378 (-) 1182 WP_002990002.1 AI-2E family transporter -
  DI45_RS05195 (DI45_05410) mutX 998436..998912 (-) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  DI45_RS05200 (DI45_05415) rfbB 999133..1000173 (-) 1041 WP_002984881.1 dTDP-glucose 4,6-dehydratase -
  DI45_RS05205 (DI45_05420) - 1000417..1001010 (-) 594 WP_002984882.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  DI45_RS05210 (DI45_05425) rfbA 1001010..1001879 (-) 870 WP_010922195.1 glucose-1-phosphate thymidylyltransferase RfbA -
  DI45_RS05215 (DI45_05430) - 1001937..1003043 (-) 1107 WP_047235327.1 NAD(P)/FAD-dependent oxidoreductase -
  DI45_RS05220 (DI45_05435) - 1003083..1003871 (-) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=105534 DI45_RS05195 WP_002984880.1 998436..998912(-) (mutX) [Streptococcus pyogenes strain NGAS743]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=105534 DI45_RS05195 WP_002984880.1 998436..998912(-) (mutX) [Streptococcus pyogenes strain NGAS743]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment