Detailed information NTG1054161

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SL319_RS13975
• Genome accession: NZ_CP169949
• Coordinates: 2772588..2773475 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN61
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2767588..2778475

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SL319_RS13945 (SL319_13945)	-	2767607..2767699 (+)	93	WP_010956583.1	hypothetical protein	-
SL319_RS13950 (SL319_13950)	-	2767807..2768304 (-)	498	WP_001065268.1	glutathione peroxidase	-
SL319_RS13955 (SL319_13955)	-	2768314..2768574 (-)	261	WP_001789910.1	hypothetical protein	-
SL319_RS13960 (SL319_13960)	-	2768956..2769069 (-)	114	WP_001791776.1	hypothetical protein	-
SL319_RS13965 (SL319_13965)	-	2769728..2771728 (-)	2001	WP_000776751.1	ABC transporter permease	-
SL319_RS13970 (SL319_13970)	-	2771725..2772480 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SL319_RS13975 (SL319_13975)	braS	2772588..2773475 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SL319_RS13980 (SL319_13980)	braR	2773486..2774151 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SL319_RS13985 (SL319_13985)	-	2774177..2774377 (-)	201	WP_000604728.1	hypothetical protein	-
SL319_RS13990 (SL319_13990)	-	2774575..2775999 (+)	1425	WP_000953744.1	alkaline phosphatase	-
SL319_RS13995 (SL319_13995)	-	2776059..2776160 (-)	102	WP_000731972.1	SE2200 family small protein	-
SL319_RS14000 (SL319_14000)	-	2776282..2776737 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SL319_RS14005 (SL319_14005)	-	2776982..2777743 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1054161 SL319_RS13975 WP_000143419.1 2772588..2773475(-) (braS) [Staphylococcus aureus strain BSN61]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1054161 SL319_RS13975 WP_000143419.1 2772588..2773475(-) (braS) [Staphylococcus aureus strain BSN61]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997