Detailed information NTG1054119

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: U2B25_RS14240
• Genome accession: NZ_CP169947
• Coordinates: 2818899..2819786 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN57-2
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2813899..2824786

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U2B25_RS14210 (U2B25_14215)	-	2813918..2814010 (+)	93	WP_010956583.1	hypothetical protein	-
U2B25_RS14215 (U2B25_14220)	-	2814118..2814615 (-)	498	WP_001065268.1	glutathione peroxidase	-
U2B25_RS14220 (U2B25_14225)	-	2814625..2814885 (-)	261	WP_001791974.1	hypothetical protein	-
U2B25_RS14225 (U2B25_14230)	-	2815267..2815380 (-)	114	Protein_2765	hypothetical protein	-
U2B25_RS14230 (U2B25_14235)	-	2816039..2818039 (-)	2001	WP_322408754.1	ABC transporter permease	-
U2B25_RS14235 (U2B25_14240)	-	2818036..2818791 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
U2B25_RS14240 (U2B25_14245)	braS	2818899..2819786 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
U2B25_RS14245 (U2B25_14250)	braR	2819797..2820462 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
U2B25_RS14250 (U2B25_14255)	-	2820488..2820688 (-)	201	WP_000604730.1	hypothetical protein	-
U2B25_RS14255 (U2B25_14260)	-	2820886..2822310 (+)	1425	WP_000953755.1	alkaline phosphatase	-
U2B25_RS14260 (U2B25_14265)	-	2822370..2822471 (-)	102	WP_000731976.1	SE2200 family small protein	-
U2B25_RS14265 (U2B25_14270)	-	2822593..2823048 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
U2B25_RS14270 (U2B25_14275)	-	2823293..2824054 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1054119 U2B25_RS14240 WP_000143425.1 2818899..2819786(-) (braS) [Staphylococcus aureus strain BSN57-2]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1054119 U2B25_RS14240 WP_000143425.1 2818899..2819786(-) (braS) [Staphylococcus aureus strain BSN57-2]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1