Detailed information NTG1052347

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: ACEPM6_RS14125
• Genome accession: NZ_CP169570
• Coordinates: 2825261..2826424 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain CIMT3
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2820261..2831424

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACEPM6_RS14095 (ACEPM6_14095)	-	2820526..2820945 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
ACEPM6_RS14100 (ACEPM6_14100)	comFC	2821019..2821708 (-)	690	WP_197538213.1	ComF family protein	Machinery gene
ACEPM6_RS14105 (ACEPM6_14105)	-	2821714..2821998 (-)	285	WP_022553866.1	late competence development ComFB family protein	-
ACEPM6_RS14110 (ACEPM6_14110)	comFA	2822056..2823441 (-)	1386	WP_022553867.1	DEAD/DEAH box helicase	Machinery gene
ACEPM6_RS14115 (ACEPM6_14115)	-	2823549..2824397 (-)	849	WP_003151387.1	DegV family protein	-
ACEPM6_RS14120 (ACEPM6_14120)	degU	2824495..2825184 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
ACEPM6_RS14125 (ACEPM6_14125)	degS	2825261..2826424 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
ACEPM6_RS14130 (ACEPM6_14130)	-	2826647..2827294 (+)	648	WP_007407485.1	YigZ family protein	-
ACEPM6_RS14135 (ACEPM6_14135)	-	2827299..2828513 (+)	1215	WP_022553868.1	LCP family protein	-
ACEPM6_RS14140 (ACEPM6_14140)	-	2828613..2829689 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
ACEPM6_RS14145 (ACEPM6_14145)	-	2829821..2831017 (-)	1197	WP_022553869.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=1052347 ACEPM6_RS14125 WP_007407484.1 2825261..2826424(-) (degS) [Bacillus velezensis strain CIMT3]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=1052347 ACEPM6_RS14125 WP_007407484.1 2825261..2826424(-) (degS) [Bacillus velezensis strain CIMT3]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951