Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ACEPM6_RS12070 Genome accession   NZ_CP169570
Coordinates   2395554..2396198 (-) Length   214 a.a.
NCBI ID   WP_014418762.1    Uniprot ID   A0A2Z4EIP2
Organism   Bacillus velezensis strain CIMT3     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 2390554..2401198
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEPM6_RS12035 (ACEPM6_12035) - 2391739..2392170 (+) 432 WP_007613424.1 Na(+)/H(+) antiporter subunit B -
  ACEPM6_RS12040 (ACEPM6_12040) - 2392170..2392511 (+) 342 WP_022553706.1 Na(+)/H(+) antiporter subunit C -
  ACEPM6_RS12045 (ACEPM6_12045) - 2392504..2393985 (+) 1482 WP_022553707.1 Na+/H+ antiporter subunit D -
  ACEPM6_RS12050 (ACEPM6_12050) - 2393991..2394467 (+) 477 WP_022553708.1 Na+/H+ antiporter subunit E -
  ACEPM6_RS12055 (ACEPM6_12055) - 2394467..2394751 (+) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  ACEPM6_RS12060 (ACEPM6_12060) mnhG 2394735..2395109 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  ACEPM6_RS12065 (ACEPM6_12065) - 2395149..2395532 (-) 384 WP_014418761.1 hotdog fold thioesterase -
  ACEPM6_RS12070 (ACEPM6_12070) comA 2395554..2396198 (-) 645 WP_014418762.1 response regulator transcription factor Regulator
  ACEPM6_RS12075 (ACEPM6_12075) comP 2396279..2398570 (-) 2292 WP_022553709.1 histidine kinase Regulator
  ACEPM6_RS12080 (ACEPM6_12080) comX 2398582..2398746 (-) 165 WP_007613432.1 competence pheromone ComX -
  ACEPM6_RS12085 (ACEPM6_12085) - 2398746..2399657 (-) 912 WP_022553710.1 polyprenyl synthetase family protein -
  ACEPM6_RS12090 (ACEPM6_12090) degQ 2399809..2399949 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  ACEPM6_RS12095 (ACEPM6_12095) - 2400415..2400756 (+) 342 WP_014418765.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24302.70 Da        Isoelectric Point: 4.9953

>NTDB_id=1052339 ACEPM6_RS12070 WP_014418762.1 2395554..2396198(-) (comA) [Bacillus velezensis strain CIMT3]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTQRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1052339 ACEPM6_RS12070 WP_014418762.1 2395554..2396198(-) (comA) [Bacillus velezensis strain CIMT3]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTTCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACACAGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGCACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z4EIP2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

85.981

100

0.86

Multiple sequence alignment