Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   ACE2AN_RS10350 Genome accession   NZ_CP169564
Coordinates   2037158..2037820 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain 6_2F1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2032158..2042820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE2AN_RS10325 - 2032308..2032574 (-) 267 WP_001278167.1 Veg family protein -
  ACE2AN_RS10330 dnaB 2032576..2033928 (-) 1353 WP_000852486.1 replicative DNA helicase -
  ACE2AN_RS10335 rplI 2033972..2034424 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  ACE2AN_RS10340 - 2034421..2036394 (-) 1974 WP_000715129.1 DHH family phosphoesterase -
  ACE2AN_RS10345 hpf 2036530..2037078 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ACE2AN_RS10350 comFC/cflB 2037158..2037820 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  ACE2AN_RS10355 comFA/cflA 2037817..2039115 (-) 1299 WP_219576538.1 DEAD/DEAH box helicase Machinery gene
  ACE2AN_RS10360 - 2039171..2039806 (+) 636 WP_000395739.1 YigZ family protein -
  ACE2AN_RS10365 cysK 2040091..2041017 (+) 927 WP_000029873.1 cysteine synthase A -
  ACE2AN_RS10370 tsf 2041138..2042178 (-) 1041 WP_000808063.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=1052226 ACE2AN_RS10350 WP_000649971.1 2037158..2037820(-) (comFC/cflB) [Streptococcus pneumoniae strain 6_2F1]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1052226 ACE2AN_RS10350 WP_000649971.1 2037158..2037820(-) (comFC/cflB) [Streptococcus pneumoniae strain 6_2F1]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment