Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACEYXE_RS05855 Genome accession   NZ_CP169521
Coordinates   1124729..1125385 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain SZ-T8     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1119729..1130385
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEYXE_RS05830 (ACEYXE_05830) oppF 1120258..1121175 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ACEYXE_RS05835 (ACEYXE_05835) - 1121282..1122478 (+) 1197 WP_012117284.1 putative glycoside hydrolase -
  ACEYXE_RS05840 (ACEYXE_05840) - 1122587..1123165 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  ACEYXE_RS05845 (ACEYXE_05845) spx 1123344..1123739 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  ACEYXE_RS05850 (ACEYXE_05850) - 1123797..1124453 (-) 657 WP_012117285.1 TerC family protein -
  ACEYXE_RS05855 (ACEYXE_05855) mecA 1124729..1125385 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  ACEYXE_RS05860 (ACEYXE_05860) - 1125536..1126696 (+) 1161 WP_012117286.1 competence protein CoiA family protein -
  ACEYXE_RS05865 (ACEYXE_05865) pepF 1126924..1128753 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  ACEYXE_RS05870 (ACEYXE_05870) - 1128791..1128958 (-) 168 WP_003155026.1 hypothetical protein -
  ACEYXE_RS05875 (ACEYXE_05875) spxH 1129244..1130146 (-) 903 WP_012117287.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=1051715 ACEYXE_RS05855 WP_003155032.1 1124729..1125385(+) (mecA) [Bacillus velezensis strain SZ-T8]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1051715 ACEYXE_RS05855 WP_003155032.1 1124729..1125385(+) (mecA) [Bacillus velezensis strain SZ-T8]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
GGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment