Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   ACEY2B_RS04000 Genome accession   NZ_CP169315
Coordinates   786171..787646 (+) Length   491 a.a.
NCBI ID   WP_015426747.1    Uniprot ID   -
Organism   Lactococcus lactis strain IFLLLBEK1     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 781171..792646
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEY2B_RS03965 (ACEY2B_03965) - 781257..782093 (+) 837 WP_015426752.1 metallophosphoesterase -
  ACEY2B_RS03970 (ACEY2B_03970) - 782206..783117 (+) 912 WP_015426751.1 CHAP domain-containing protein -
  ACEY2B_RS03975 (ACEY2B_03975) - 783344..783706 (+) 363 WP_042230481.1 TIGR02328 family protein -
  ACEY2B_RS03980 (ACEY2B_03980) - 783788..784252 (+) 465 WP_015426749.1 hypothetical protein -
  ACEY2B_RS03985 (ACEY2B_03985) - 784408..784653 (+) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  ACEY2B_RS03990 (ACEY2B_03990) - 784784..785314 (+) 531 WP_015426748.1 DUF177 domain-containing protein -
  ACEY2B_RS03995 (ACEY2B_03995) covR 785470..786162 (+) 693 WP_003130756.1 response regulator transcription factor Regulator
  ACEY2B_RS04000 (ACEY2B_04000) covS 786171..787646 (+) 1476 WP_015426747.1 HAMP domain-containing histidine kinase Regulator
  ACEY2B_RS04005 (ACEY2B_04005) - 787829..789070 (+) 1242 WP_015426746.1 ammonium transporter -
  ACEY2B_RS04010 (ACEY2B_04010) - 789202..789543 (+) 342 WP_010906046.1 P-II family nitrogen regulator -
  ACEY2B_RS04015 (ACEY2B_04015) murD 789875..791227 (+) 1353 WP_015426745.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  ACEY2B_RS04020 (ACEY2B_04020) murG 791437..792510 (+) 1074 WP_003130746.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -

Sequence

Protein


Download         Length: 491 a.a.        Molecular weight: 56268.17 Da        Isoelectric Point: 4.7402

>NTDB_id=1050479 ACEY2B_RS04000 WP_015426747.1 786171..787646(+) (covS) [Lactococcus lactis strain IFLLLBEK1]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIIAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNQALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVYEDEQFVITSVSDKGIGISEEDIDHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide


Download         Length: 1476 bp        

>NTDB_id=1050479 ACEY2B_RS04000 WP_015426747.1 786171..787646(+) (covS) [Lactococcus lactis strain IFLLLBEK1]
ATGAAAAAATTATTTACTTTCAATAAGAAAAAAGAGACGGTAGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATCAGTTCTT
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGCACACGGAAAGCATTTTATATTTATGATTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAGAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTAGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTATCGCTCAGTTGATTGGTTATTTCATGGCTAATTACTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGCGGAGATGAAATCGAAGAGTTGGCTCACGTTTACAATGATATGATGTTGAAGATGAAGGCATATCTTGAACAGCA
AAATCGGTTTGTTTCTGATGTTTCTCACGAGTTAAGAACACCCTTAGCTGTCTTGGATGGACATATTAACTTGCTGAATC
GATGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGTCTTGAAAATGTTGATTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCAGGCCCTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGCTTAAGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGTGATTACTGTTTATGAGGATGAACAGTTTGTGATTACGAGTGTATCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTGATCATCTTTTTGAACGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTACCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

ArlS sensor domain (ArlS_N)

(54-185)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-489)

HAMP domain (HAMP)

(208-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

98.982

100

0.99

Multiple sequence alignment