Detailed information NTG1049112

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK32_RS14390
• Genome accession: NZ_CP168975
• Coordinates: 2831270..2832157 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CUBIST-8
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2826270..2837157

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK32_RS14360 (ACCK32_14360)	-	2826289..2826381 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK32_RS14365 (ACCK32_14365)	-	2826489..2826986 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK32_RS14370 (ACCK32_14370)	-	2826996..2827256 (-)	261	WP_001789910.1	hypothetical protein	-
ACCK32_RS14375 (ACCK32_14375)	-	2827638..2827751 (-)	114	WP_001791776.1	hypothetical protein	-
ACCK32_RS14380 (ACCK32_14380)	-	2828410..2830410 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACCK32_RS14385 (ACCK32_14385)	-	2830407..2831162 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK32_RS14390 (ACCK32_14390)	braS	2831270..2832157 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK32_RS14395 (ACCK32_14395)	braR	2832168..2832833 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK32_RS14400 (ACCK32_14400)	-	2832859..2833059 (-)	201	WP_000604728.1	hypothetical protein	-
ACCK32_RS14405 (ACCK32_14405)	-	2833257..2834681 (+)	1425	WP_000953744.1	alkaline phosphatase	-
ACCK32_RS14410 (ACCK32_14410)	-	2834741..2834842 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACCK32_RS14415 (ACCK32_14415)	-	2834964..2835419 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK32_RS14420 (ACCK32_14420)	-	2835664..2836425 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1049112 ACCK32_RS14390 WP_000143419.1 2831270..2832157(-) (braS) [Staphylococcus aureus strain CUBIST-8]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1049112 ACCK32_RS14390 WP_000143419.1 2831270..2832157(-) (braS) [Staphylococcus aureus strain CUBIST-8]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997