Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACCK32_RS11235 Genome accession   NZ_CP168975
Coordinates   2211674..2212453 (+) Length   259 a.a.
NCBI ID   WP_000688495.1    Uniprot ID   -
Organism   Staphylococcus aureus strain CUBIST-8     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2206674..2217453
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACCK32_RS11205 (ACCK32_11205) - 2206893..2207519 (+) 627 WP_000522384.1 nitroreductase family protein -
  ACCK32_RS11210 (ACCK32_11210) - 2207880..2208665 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  ACCK32_RS11215 (ACCK32_11215) hld 2209262..2209342 (-) 81 WP_000046022.1 delta-hemolysin -
  ACCK32_RS11220 (ACCK32_11220) agrB 2209632..2210201 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  ACCK32_RS11225 (ACCK32_11225) agrD 2210198..2210338 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACCK32_RS11230 (ACCK32_11230) agrC 2210363..2211655 (+) 1293 WP_001549202.1 quorum-sensing sensor histidine kinase AgrC -
  ACCK32_RS11235 (ACCK32_11235) agrA 2211674..2212453 (+) 780 WP_000688495.1 quorum-sensing response regulator AgrA Regulator
  ACCK32_RS11240 (ACCK32_11240) - 2212461..2212568 (+) 108 WP_001790167.1 hypothetical protein -
  ACCK32_RS11245 (ACCK32_11245) - 2212756..2213715 (-) 960 WP_001253312.1 carbohydrate kinase -
  ACCK32_RS11250 (ACCK32_11250) - 2213712..2215196 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  ACCK32_RS11255 (ACCK32_11255) - 2215345..2216295 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 30361.82 Da        Isoelectric Point: 6.8880

>NTDB_id=1049109 ACCK32_RS11235 WP_000688495.1 2211674..2212453(+) (agrA) [Staphylococcus aureus strain CUBIST-8]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKYNK
IIKSVNGVFNCKSCWILTR

Nucleotide


Download         Length: 780 bp        

>NTDB_id=1049109 ACCK32_RS11235 WP_000688495.1 2211674..2212453(+) (agrA) [Staphylococcus aureus strain CUBIST-8]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAATATAATAAG
ATAATAAAGTCAGTTAACGGCGTATTCAATTGTAAATCTTGTTGGATTTTAACAAGATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-242)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

91.506

0.915

Multiple sequence alignment