Detailed information NTG0104745

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: NTHI723_RS03725
• Genome accession: NZ_CP007472
• Coordinates: 779589..782159 (-)
• Length: 856 a.a.
• NCBI ID: WP_011272249.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain 723
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 774589..787159

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NTHI723_RS03700 (NTHI723_00746)	pdxH	774683..775315 (-)	633	WP_040035016.1	pyridoxamine 5'-phosphate oxidase	-
NTHI723_RS03705 (NTHI723_00747)	-	775508..776215 (+)	708	WP_005693208.1	7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter	-
NTHI723_RS03715 (NTHI723_00748)	rnr	776407..778755 (+)	2349	WP_044364527.1	ribonuclease R	-
NTHI723_RS03720 (NTHI723_00749)	rlmB	778811..779551 (+)	741	WP_011272250.1	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	-
NTHI723_RS03725 (NTHI723_00750)	clpC	779589..782159 (-)	2571	WP_011272249.1	ATP-dependent chaperone ClpB	Regulator
NTHI723_RS03730 (NTHI723_00751)	-	782287..782850 (-)	564	WP_011272248.1	5-formyltetrahydrofolate cyclo-ligase	-
NTHI723_RS03735 (NTHI723_00752)	-	783173..783475 (-)	303	WP_005651366.1	cell division protein ZapA	-
NTHI723_RS03740 (NTHI723_00753)	polA	783624..786416 (+)	2793	WP_044364528.1	DNA polymerase I	-
NTHI723_RS03745 (NTHI723_00754)	-	786431..786673 (+)	243	Protein_754	serine dehydratase subunit alpha family protein	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 95674.09 Da
• Isoelectric Point: 5.0182

>NTDB_id=104745 NTHI723_RS03725 WP_011272249.1 779589..782159(-) (clpC) [Haemophilus influenzae strain 723]
MNIEKFTTKFQEALSEAQSLAIGKDNQFIEPVHLLTALLNQQGGSIAPILTASGVNVALLRNELKTELNKLPQVIGNGGD
VQLSRQLINLLNLCDKFAQQNQDKFISSELFLLAALEERGTISDILKKCGAKKEQISQAIQHIRGGQNVNDQNAEESRQA
LEKYTIDLTARAESGKLDPVIGRDEEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSL
DMGALIAGAKYRGEFEERLKAVLNELSKEEGRVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYR
QYIEKDAALERRFQKVFVDEPSVEDTIAILRGLKERYEIHHHVDITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASS
IRMEIDSKPEPLDRLERRIIQLKLEQQALQKEEDEASRKRLEMLEKELAEKEREYAELEEVWKSEKATLSGSQHIKQELD
TAKTELEQARRAGDLAKMSELQYGRIPALEKQLEQAETSEGKEMTLLRYRVTDEEIAEVLSKATGIPVSKMMEGEKEKLL
RMEDELHKRVIGQEEAVDAVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLAKFLFDSEDAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHADVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSDLIQGNKDESYSEMKALVMSVVSQHFRPEFINRIDETVVFHPLGKENIRAIASIQLERLAKRMETRGYELVFTDALLD
FIGEVGYDPIYGARPLKRAIQQEIENSLAQQILSGALLPGKVVTIDYANAEVQARQ

Nucleotide

• Length: 2571 bp

>NTDB_id=104745 NTHI723_RS03725 WP_011272249.1 779589..782159(-) (clpC) [Haemophilus influenzae strain 723]
ATGAACATTGAAAAATTTACGACAAAATTCCAAGAAGCGTTAAGCGAAGCACAATCACTTGCTATCGGAAAAGACAATCA
ATTTATTGAACCCGTGCATTTATTGACCGCACTTTTAAATCAACAGGGCGGCTCTATTGCGCCAATTTTGACAGCAAGTG
GCGTAAATGTGGCTTTATTGCGTAATGAATTAAAGACAGAACTAAATAAATTGCCGCAAGTGATTGGCAATGGTGGAGAT
GTACAACTTTCACGCCAGCTTATTAATTTACTTAATCTATGCGATAAATTCGCACAGCAAAACCAAGATAAATTTATTTC
GAGCGAATTGTTTTTGCTTGCAGCTTTAGAAGAACGAGGAACGATCAGCGATATTTTGAAAAAGTGCGGTGCGAAAAAAG
AACAAATTTCGCAAGCTATTCAGCACATTAGAGGGGGACAAAACGTGAACGATCAAAATGCAGAAGAAAGCAGACAAGCT
CTTGAAAAATATACGATTGATTTAACCGCTCGTGCAGAAAGTGGCAAACTTGATCCTGTAATTGGGCGTGATGAAGAAAT
TCGTCGAGCCATTCAAGTATTACAACGTCGTACCAAAAATAACCCTGTGTTAATTGGTGAACCAGGTGTAGGGAAAACGG
CGATTGTCGAAGGCTTGGCACAGCGTATCGTAAACGGCGAAGTGCCAGAAGGTTTGAAAAATAAACGTGTGCTTTCATTA
GATATGGGCGCATTGATTGCTGGTGCAAAATATCGCGGAGAATTTGAAGAACGTTTAAAAGCGGTGCTCAATGAACTTTC
TAAAGAAGAAGGTCGCGTGATCCTCTTTATTGATGAAATTCATACTATGGTCGGCGCGGGTAAAACCGATGGTGCGATGG
ATGCGGGTAACTTATTAAAACCAAGTTTAGCGCGCGGTGAATTACATTGCGTGGGTGCAACAACGTTAGACGAATATCGT
CAATATATCGAAAAAGATGCCGCACTTGAGCGCCGTTTCCAAAAAGTATTTGTGGACGAACCAAGTGTAGAAGATACCAT
TGCTATCTTACGTGGTTTGAAAGAACGCTATGAAATTCATCATCACGTGGATATTACTGACCCTGCGATTGTCGCTGCCG
CAACGCTTTCACATCGTTATATTTCCGATCGTCAATTGCCGGATAAAGCCATTGATTTGATCGATGAAGCGGCGTCTAGC
ATTCGTATGGAAATAGATTCTAAACCTGAACCGCTTGATCGCCTTGAACGTCGAATTATCCAATTAAAATTGGAACAACA
GGCATTACAAAAAGAAGAAGACGAAGCAAGTCGCAAACGTTTAGAAATGTTAGAGAAAGAATTGGCTGAAAAAGAACGTG
AATACGCCGAACTTGAAGAAGTATGGAAATCTGAAAAAGCAACGCTTTCTGGCTCTCAACATATTAAACAAGAATTAGAT
ACTGCAAAAACCGAACTAGAACAAGCTCGTCGTGCGGGTGATTTAGCGAAAATGTCAGAGTTGCAATATGGACGCATCCC
TGCTCTTGAAAAGCAACTCGAGCAAGCTGAAACCAGCGAAGGAAAAGAAATGACGCTTTTACGCTATCGTGTCACGGATG
AAGAAATCGCAGAAGTGCTTTCTAAAGCCACAGGTATTCCTGTATCCAAAATGATGGAAGGCGAGAAAGAAAAACTCTTG
CGCATGGAAGATGAACTACATAAACGAGTGATTGGTCAAGAAGAAGCAGTTGATGCGGTAGCAAACGCGATTCGTCGTAG
TCGTGCTGGTCTTTCCGATCCTAATCGCCCAATTGGTTCATTCTTGTTCCTAGGGCCAACAGGTGTGGGTAAAACAGAGC
TTTGCAAAACTTTGGCTAAATTCTTGTTTGATAGTGAAGATGCGATGGTGCGCATTGATATGTCAGAGTTTATGGAAAAG
CACAGTGTCTCTCGTTTAGTGGGTGCGCCTCCAGGCTATGTCGGCTATGAAGAAGGCGGTTATTTAACTGAGGCTGTTCG
TCGTCGTCCATATTCAGTGATCTTATTAGATGAAGTTGAAAAAGCCCATGCGGATGTATTCAATATCTTATTACAAGTAT
TGGATGATGGTCGTTTAACTGACGGGCAAGGTCGTACTGTGGACTTCCGTAATACGGTGGTAATTATGACCTCTAACTTG
GGTTCTGATTTAATCCAAGGTAACAAAGACGAAAGCTATAGCGAAATGAAAGCCTTAGTGATGTCAGTGGTAAGCCAACA
TTTCCGTCCCGAATTCATCAACCGTATTGACGAAACTGTGGTATTCCATCCGCTTGGTAAAGAGAATATTCGTGCGATTG
CAAGTATCCAATTAGAACGCTTAGCAAAACGTATGGAAACTCGTGGCTATGAATTAGTGTTTACCGACGCTTTATTAGAT
TTCATTGGTGAAGTGGGGTATGACCCAATTTATGGTGCACGTCCATTGAAACGTGCTATTCAACAAGAGATCGAAAACAG
CTTGGCACAACAAATTCTATCTGGTGCGTTATTACCTGGTAAGGTTGTTACCATTGATTACGCCAACGCAGAAGTTCAAG
CTAGACAATAG

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (765-845)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-758)

• AAA lid domain (AAA_lid_9) (342-443)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.181	100	0.479
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.572	100	0.447
clpE	Streptococcus pneumoniae TIGR4	49.12	79.673	0.391
clpE	Streptococcus pneumoniae R6	48.311	79.556	0.384
clpE	Streptococcus pneumoniae Rx1	48.311	79.556	0.384
clpE	Streptococcus pneumoniae D39	48.311	79.556	0.384
clpE	Streptococcus mutans UA159	47.724	79.556	0.38
clpC	Lactococcus lactis subsp. cremoris KW2	45.467	82.477	0.375