Detailed information NTG1045748

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: RCP39_RS12825
• Genome accession: NZ_OY725974
• Coordinates: 2567921..2570029 (+)
• Length: 702 a.a.
• NCBI ID: WP_307734274.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain Sa_BGR_NF1 isolate Sa_BGR_NF1
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2562921..2575029

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RCP39_RS12800 (SAUR1852_12680)	-	2562942..2563160 (+)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-
RCP39_RS12805 (SAUR1852_12690)	-	2563548..2563979 (+)	432	WP_000875614.1	CHAP domain-containing protein	-
RCP39_RS12810 (SAUR1852_12695)	-	2564119..2565399 (-)	1281	WP_001191004.1	hydroxymethylglutaryl-CoA reductase, degradative	-
RCP39_RS12815 (SAUR1852_12700)	-	2565654..2566820 (+)	1167	WP_000151980.1	hydroxymethylglutaryl-CoA synthase	-
RCP39_RS12820 (SAUR1852_12705)	-	2566991..2567512 (-)	522	WP_000384652.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
RCP39_RS12825 (SAUR1852_12710)	clpE	2567921..2570029 (+)	2109	WP_307734274.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
RCP39_RS12830 (SAUR1852_12715)	-	2570096..2570266 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
RCP39_RS12835 (SAUR1852_12720)	feoB	2570279..2572273 (-)	1995	WP_000432889.1	ferrous iron transport protein B	-
RCP39_RS12840 (SAUR1852_12725)	-	2572285..2572512 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 77995.45 Da
• Isoelectric Point: 4.6294

>NTDB_id=1045748 RCP39_RS12825 WP_307734274.1 2567921..2570029(+) (clpE) [Staphylococcus aureus strain Sa_BGR_NF1 isolate Sa_BGR_NF1]
MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGKRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDTEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=1045748 RCP39_RS12825 WP_307734274.1 2567921..2570029(+) (clpE) [Staphylococcus aureus strain Sa_BGR_NF1 isolate Sa_BGR_NF1]
ATGAATAACGGTTTTTTCAATAGCGACTTTGATTCAATTTTTCGAAGAATGATGCAAGATATGCAAGGTTCAAATCAAGT
CGGTAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGGCAACAAGGTGGCAACGGCAATTAT
TTAGAACAAATTGGCCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAAT
TCAAGAAACTGCTGAAGTTTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCACAGGCAATCGTTGAAGGGAATGTACCTGCAGCCATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAA
ATCTTCACAAAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAGATTTCTATTATTGGTGCAACAACACAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAGTGCTAAAGA
TACTGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTCAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ATAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCACGTGCAATTCGCCGTAATCGCGCTGGGTTTGATGACGGCAAACGTCCAATTGGTAGTTTCC
TATTTGTCGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTTATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTATTACTACAAGTGATGGATGATGGTAATTTGACTGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCATTATTTGTACGTCAAACGCTGGTTTTGGTAACGGCAATGACACTGAAGAAAAAGACATTAT
GCATGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTACAAGATATCGTCAACTTATTATTAGACGATGTACAAGTTACATTAGATAAAAAAGGTATTACGATGGACGTT
TCTCAAGATGCGAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGAATTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (264-363)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.678	91.595	0.446
clpE	Streptococcus pneumoniae TIGR4	48.136	87.892	0.423
clpE	Streptococcus pneumoniae Rx1	48.136	87.892	0.423
clpE	Streptococcus pneumoniae D39	48.136	87.892	0.423
clpE	Streptococcus pneumoniae R6	48.136	87.892	0.423
clpC	Lactococcus lactis subsp. cremoris KW2	46.361	90.028	0.417
clpC	Bacillus subtilis subsp. subtilis str. 168	44.717	93.02	0.416
clpC	Streptococcus thermophilus LMD-9	44.392	90.171	0.4
clpC	Streptococcus thermophilus LMG 18311	44.076	90.171	0.397
clpC	Streptococcus pneumoniae TIGR4	44.013	88.034	0.387
clpC	Streptococcus pneumoniae Rx1	44.013	88.034	0.387
clpC	Streptococcus pneumoniae D39	44.013	88.034	0.387
clpC	Streptococcus mutans UA159	43.74	87.607	0.383
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.294	92.45	0.382