Detailed information NTG0104563

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: CH52_RS10980
• Genome accession: NZ_CP007454
• Coordinates: 2126713..2127987 (-)
• Length: 424 a.a.
• NCBI ID: WP_001279338.1
• Uniprot ID: A0A0H2XGV4
• Organism: Staphylococcus aureus strain 502A isolate RN6607
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2121713..2132987

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CH52_RS10965	-	2123998..2124090 (+)	93	WP_031761401.1	hypothetical protein	-
CH52_RS10970 (CH52_10460)	-	2124070..2124975 (-)	906	WP_000184370.1	transglycosylase domain-containing protein	-
CH52_RS10975 (CH52_10465)	tyrS	2125357..2126619 (+)	1263	WP_000186029.1	tyrosine--tRNA ligase	-
CH52_RS10980 (CH52_10470)	htrA	2126713..2127987 (-)	1275	WP_001279338.1	S1C family serine protease	Regulator
CH52_RS10985 (CH52_10475)	-	2128159..2128776 (+)	618	WP_000287588.1	lysophospholipid acyltransferase family protein	-
CH52_RS10990 (CH52_10480)	nagE	2128904..2130370 (+)	1467	WP_000276367.1	N-acetylglucosamine-specific PTS transporter subunit IIBC	-
CH52_RS10995 (CH52_10485)	-	2130477..2131607 (+)	1131	WP_000721699.1	HAD family hydrolase	-
CH52_RS11000	-	2131568..2131663 (-)	96	WP_031761395.1	hypothetical protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 45802.98 Da
• Isoelectric Point: 9.9696

>NTDB_id=104563 CH52_RS10980 WP_001279338.1 2126713..2127987(-) (htrA) [Staphylococcus aureus strain 502A isolate RN6607]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide

• Length: 1275 bp

>NTDB_id=104563 CH52_RS10980 WP_001279338.1 2126713..2127987(-) (htrA) [Staphylococcus aureus strain 502A isolate RN6607]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATTATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTTCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCTGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTTGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGCGAACGTACGATTGACGCTGAGACAACTGGTGGCAATACAAAA
GTTAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATCGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATTGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATTCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCCAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAACCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (125-269)

• PDZ domain (PDZ_2) (307-397)

3D structure

• AlphaFold DB: A0A0H2XGV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	39.055	94.811	0.37