Detailed information NTG1045542

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: D712_RS13615
• Genome accession: NZ_CP168754
• Coordinates: 2718389..2719276 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain D712
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2713389..2724276

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D712_RS13585 (D712_013585)	-	2713408..2713500 (+)	93	WP_010956583.1	hypothetical protein	-
D712_RS13590 (D712_013590)	-	2713608..2714105 (-)	498	WP_001065268.1	glutathione peroxidase	-
D712_RS13595 (D712_013595)	-	2714115..2714375 (-)	261	WP_001796813.1	hypothetical protein	-
D712_RS13600 (D712_013600)	-	2714757..2714870 (-)	114	Protein_2637	hypothetical protein	-
D712_RS13605 (D712_013605)	-	2715529..2717529 (-)	2001	WP_000776750.1	ABC transporter permease	-
D712_RS13610 (D712_013610)	-	2717526..2718281 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
D712_RS13615 (D712_013615)	braS	2718389..2719276 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
D712_RS13620 (D712_013620)	braR	2719287..2719952 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
D712_RS13625 (D712_013625)	-	2719978..2720178 (-)	201	WP_000604730.1	hypothetical protein	-
D712_RS13630 (D712_013630)	-	2720376..2721800 (+)	1425	WP_000953755.1	alkaline phosphatase	-
D712_RS13635 (D712_013635)	-	2721860..2721961 (-)	102	WP_000731976.1	SE2200 family small protein	-
D712_RS13640 (D712_013640)	-	2722083..2722538 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
D712_RS13645 (D712_013645)	-	2722783..2723544 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1045542 D712_RS13615 WP_000143425.1 2718389..2719276(-) (braS) [Staphylococcus aureus strain D712]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1045542 D712_RS13615 WP_000143425.1 2718389..2719276(-) (braS) [Staphylococcus aureus strain D712]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1