Detailed information NTG1045254

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACEOOE_RS09510
• Genome accession: NZ_CP168717
• Coordinates: 1939162..1940205 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain C96
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1934162..1945205

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACEOOE_RS09480 (ACEOOE_09480)	-	1934583..1935839 (-)	1257	WP_001795108.1	aminopeptidase	-
ACEOOE_RS09485 (ACEOOE_09485)	-	1935842..1936042 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACEOOE_RS09490 (ACEOOE_09490)	-	1936189..1936653 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACEOOE_RS09495 (ACEOOE_09495)	-	1936660..1936935 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACEOOE_RS09500 (ACEOOE_09500)	-	1937213..1938430 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
ACEOOE_RS09505 (ACEOOE_09505)	vraR	1938543..1939172 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACEOOE_RS09510 (ACEOOE_09510)	vraS	1939162..1940205 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACEOOE_RS09515 (ACEOOE_09515)	liaF	1940202..1940903 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACEOOE_RS09520 (ACEOOE_09520)	-	1940918..1941304 (-)	387	WP_001110179.1	hypothetical protein	-
ACEOOE_RS09525 (ACEOOE_09525)	map	1941521..1942279 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACEOOE_RS09530 (ACEOOE_09530)	-	1942751..1943737 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
ACEOOE_RS09535 (ACEOOE_09535)	-	1944168..1944581 (-)	414	WP_001557448.1	hypothetical protein	-
ACEOOE_RS09540 (ACEOOE_09540)	-	1944610..1944720 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1045254 ACEOOE_RS09510 WP_001017131.1 1939162..1940205(-) (vraS) [Staphylococcus aureus strain C96]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1045254 ACEOOE_RS09510 WP_001017131.1 1939162..1940205(-) (vraS) [Staphylococcus aureus strain C96]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1