Detailed information NTG1044401

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACEPOT_RS12550
• Genome accession: NZ_CP168499
• Coordinates: 2560102..2561145 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain J2
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2555102..2566145

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACEPOT_RS12520 (ACEPOT_12520)	-	2555530..2556786 (-)	1257	WP_001793428.1	aminopeptidase	-
ACEPOT_RS12525 (ACEPOT_12525)	-	2556789..2556989 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACEPOT_RS12530 (ACEPOT_12530)	-	2557136..2557600 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACEPOT_RS12535 (ACEPOT_12535)	-	2557607..2557882 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACEPOT_RS12540 (ACEPOT_12540)	-	2558160..2559371 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
ACEPOT_RS12545 (ACEPOT_12545)	vraR	2559483..2560112 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACEPOT_RS12550 (ACEPOT_12550)	vraS	2560102..2561145 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACEPOT_RS12555 (ACEPOT_12555)	liaF	2561142..2561843 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACEPOT_RS12560 (ACEPOT_12560)	-	2561858..2562244 (-)	387	WP_001110179.1	hypothetical protein	-
ACEPOT_RS12565 (ACEPOT_12565)	map	2562461..2563219 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACEPOT_RS12570 (ACEPOT_12570)	-	2563750..2564736 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
ACEPOT_RS12575 (ACEPOT_12575)	-	2565226..2565639 (-)	414	WP_001837236.1	hypothetical protein	-
ACEPOT_RS12580 (ACEPOT_12580)	-	2565668..2565779 (-)	112	Protein_2438	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1044401 ACEPOT_RS12550 WP_001017131.1 2560102..2561145(-) (vraS) [Staphylococcus aureus strain J2]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1044401 ACEPOT_RS12550 WP_001017131.1 2560102..2561145(-) (vraS) [Staphylococcus aureus strain J2]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1