Detailed information NTG1044329

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACEPOU_RS03050
• Genome accession: NZ_CP168498
• Coordinates: 571362..572405 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain J22
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 566362..577405

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACEPOU_RS03020 (ACEPOU_03020)	-	566790..566900 (+)	111	WP_001790257.1	hypothetical protein	-
ACEPOU_RS03025 (ACEPOU_03025)	-	566929..567342 (+)	414	WP_001670387.1	hypothetical protein	-
ACEPOU_RS03030 (ACEPOU_03030)	-	567773..568759 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
ACEPOU_RS03035 (ACEPOU_03035)	map	569288..570046 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACEPOU_RS03040 (ACEPOU_03040)	-	570263..570649 (+)	387	WP_001110179.1	hypothetical protein	-
ACEPOU_RS03045 (ACEPOU_03045)	liaF	570664..571365 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACEPOU_RS03050 (ACEPOU_03050)	vraS	571362..572405 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACEPOU_RS03055 (ACEPOU_03055)	vraR	572395..573024 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACEPOU_RS03060 (ACEPOU_03060)	-	573137..574354 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
ACEPOU_RS03065 (ACEPOU_03065)	-	574632..574907 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
ACEPOU_RS03070 (ACEPOU_03070)	-	574914..575378 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACEPOU_RS03075 (ACEPOU_03075)	-	575525..575725 (+)	201	WP_000180460.1	DUF1128 family protein	-
ACEPOU_RS03080 (ACEPOU_03080)	-	575728..576984 (+)	1257	WP_075583716.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1044329 ACEPOU_RS03050 WP_001017131.1 571362..572405(+) (vraS) [Staphylococcus aureus strain J22]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1044329 ACEPOU_RS03050 WP_001017131.1 571362..572405(+) (vraS) [Staphylococcus aureus strain J22]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1