Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACEPOS_RS09770 Genome accession   NZ_CP168497
Coordinates   2012331..2013047 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain J23     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2007331..2018047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEPOS_RS09750 (ACEPOS_09750) - 2008425..2009375 (+) 951 WP_020977433.1 LacI family DNA-binding transcriptional regulator -
  ACEPOS_RS09755 (ACEPOS_09755) - 2009524..2011008 (+) 1485 WP_000141418.1 sucrose-6-phosphate hydrolase -
  ACEPOS_RS09760 (ACEPOS_09760) - 2011005..2011964 (+) 960 WP_086155576.1 carbohydrate kinase -
  ACEPOS_RS09765 (ACEPOS_09765) - 2012152..2012259 (-) 108 WP_041204320.1 hypothetical protein -
  ACEPOS_RS09770 (ACEPOS_09770) agrA 2012331..2013047 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACEPOS_RS09775 (ACEPOS_09775) agrC 2013066..2014358 (-) 1293 WP_373441711.1 quorum-sensing sensor histidine kinase AgrC -
  ACEPOS_RS09780 (ACEPOS_09780) agrD 2014383..2014523 (-) 141 WP_001094303.1 cyclic lactone autoinducer peptide AgrD -
  ACEPOS_RS09785 (ACEPOS_09785) - 2014525..2015088 (-) 564 WP_001105715.1 accessory gene regulator AgrB -
  ACEPOS_RS09790 (ACEPOS_09790) hld 2015378..2015458 (+) 81 WP_000046023.1 delta-hemolysin -
  ACEPOS_RS09795 (ACEPOS_09795) - 2016057..2016842 (-) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  ACEPOS_RS09800 (ACEPOS_09800) - 2017203..2017829 (-) 627 WP_000522383.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1044302 ACEPOS_RS09770 WP_000688492.1 2012331..2013047(-) (agrA) [Staphylococcus aureus strain J23]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1044302 ACEPOS_RS09770 WP_000688492.1 2012331..2013047(-) (agrA) [Staphylococcus aureus strain J23]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment