Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   ACEPOS_RS06590 Genome accession   NZ_CP168497
Coordinates   1382588..1383253 (+) Length   221 a.a.
NCBI ID   WP_000697883.1    Uniprot ID   A0A5F0HLH2
Organism   Staphylococcus aureus strain J23     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1377588..1388253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEPOS_RS06565 (ACEPOS_06565) - 1378996..1379757 (+) 762 WP_000323443.1 alpha/beta hydrolase family protein -
  ACEPOS_RS06570 (ACEPOS_06570) - 1380002..1380457 (+) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  ACEPOS_RS06575 (ACEPOS_06575) - 1380579..1380680 (+) 102 WP_000731972.1 SE2200 family small protein -
  ACEPOS_RS06580 (ACEPOS_06580) - 1380740..1382164 (-) 1425 WP_271019555.1 alkaline phosphatase -
  ACEPOS_RS06585 (ACEPOS_06585) - 1382362..1382562 (+) 201 WP_000604727.1 hypothetical protein -
  ACEPOS_RS06590 (ACEPOS_06590) braR 1382588..1383253 (+) 666 WP_000697883.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  ACEPOS_RS06595 (ACEPOS_06595) braS 1383264..1384151 (+) 888 WP_271019560.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  ACEPOS_RS06600 (ACEPOS_06600) - 1384259..1385014 (+) 756 WP_271019561.1 ABC transporter ATP-binding protein -
  ACEPOS_RS06605 (ACEPOS_06605) - 1385011..1387011 (+) 2001 WP_020977629.1 ABC transporter permease -
  ACEPOS_RS06610 (ACEPOS_06610) - 1387670..1387783 (+) 114 WP_072468803.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25433.52 Da        Isoelectric Point: 4.7961

>NTDB_id=1044297 ACEPOS_RS06590 WP_000697883.1 1382588..1383253(+) (braR) [Staphylococcus aureus strain J23]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=1044297 ACEPOS_RS06590 WP_000697883.1 1382588..1383253(+) (braR) [Staphylococcus aureus strain J23]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATTCTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HLH2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995

Multiple sequence alignment