Detailed information NTG1044189

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK33_RS14010
• Genome accession: NZ_CP168442
• Coordinates: 2769014..2769901 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain J03
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2764014..2774901

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK33_RS13980 (ACCK33_13980)	-	2764033..2764125 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK33_RS13985 (ACCK33_13985)	-	2764233..2764730 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK33_RS13990 (ACCK33_13990)	-	2764740..2765000 (-)	261	WP_001789910.1	hypothetical protein	-
ACCK33_RS13995 (ACCK33_13995)	-	2765382..2765495 (-)	114	WP_011447078.1	hypothetical protein	-
ACCK33_RS14000 (ACCK33_14000)	-	2766154..2768154 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACCK33_RS14005 (ACCK33_14005)	-	2768151..2768906 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK33_RS14010 (ACCK33_14010)	braS	2769014..2769901 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK33_RS14015 (ACCK33_14015)	braR	2769912..2770577 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK33_RS14020 (ACCK33_14020)	-	2770603..2770803 (-)	201	WP_000604728.1	hypothetical protein	-
ACCK33_RS14025 (ACCK33_14025)	-	2771001..2772425 (+)	1425	WP_000953744.1	alkaline phosphatase	-
ACCK33_RS14030 (ACCK33_14030)	-	2772485..2772586 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACCK33_RS14035 (ACCK33_14035)	-	2772708..2773163 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK33_RS14040 (ACCK33_14040)	-	2773408..2774169 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1044189 ACCK33_RS14010 WP_000143419.1 2769014..2769901(-) (braS) [Staphylococcus aureus strain J03]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1044189 ACCK33_RS14010 WP_000143419.1 2769014..2769901(-) (braS) [Staphylococcus aureus strain J03]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997