Detailed information NTG1044183

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACCK33_RS10090
• Genome accession: NZ_CP168442
• Coordinates: 2025368..2026411 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain J03
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2020368..2031411

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK33_RS10060 (ACCK33_10060)	-	2020786..2022042 (-)	1257	WP_001795438.1	aminopeptidase	-
ACCK33_RS10065 (ACCK33_10065)	-	2022045..2022245 (-)	201	WP_000180461.1	DUF1128 family protein	-
ACCK33_RS10070 (ACCK33_10070)	-	2022392..2022856 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACCK33_RS10075 (ACCK33_10075)	-	2022863..2023138 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACCK33_RS10080 (ACCK33_10080)	-	2023416..2024633 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
ACCK33_RS10085 (ACCK33_10085)	vraR	2024749..2025378 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
ACCK33_RS10090 (ACCK33_10090)	vraS	2025368..2026411 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACCK33_RS10095 (ACCK33_10095)	liaF	2026408..2027109 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACCK33_RS10100 (ACCK33_10100)	-	2027124..2027510 (-)	387	WP_001110179.1	hypothetical protein	-
ACCK33_RS10105 (ACCK33_10105)	map	2027727..2028485 (-)	759	WP_138642981.1	type I methionyl aminopeptidase	-
ACCK33_RS10110 (ACCK33_10110)	-	2029072..2030058 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
ACCK33_RS10115 (ACCK33_10115)	-	2030489..2030902 (-)	414	WP_001549145.1	hypothetical protein	-
ACCK33_RS10120 (ACCK33_10120)	-	2030931..2031041 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1044183 ACCK33_RS10090 WP_001017131.1 2025368..2026411(-) (vraS) [Staphylococcus aureus strain J03]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1044183 ACCK33_RS10090 WP_001017131.1 2025368..2026411(-) (vraS) [Staphylococcus aureus strain J03]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1