Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   ACEPOY_RS01705 Genome accession   NZ_CP168437
Coordinates   368952..369626 (-) Length   224 a.a.
NCBI ID   WP_000866106.1    Uniprot ID   -
Organism   Staphylococcus aureus strain P3L30A     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 358227..372937 368952..369626 within 0
IScluster/Tn 359996..374108 368952..369626 within 0


Gene organization within MGE regions


Location: 358227..374108
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEPOY_RS01625 (ACEPOY_01625) - 358630..358893 (-) 264 WP_001055897.1 helix-turn-helix transcriptional regulator -
  ACEPOY_RS01630 (ACEPOY_01630) - 359193..359444 (+) 252 WP_000466743.1 GlsB/YeaQ/YmgE family stress response membrane protein -
  ACEPOY_RS01635 (ACEPOY_01635) - 359487..359696 (-) 210 WP_000211678.1 hypothetical protein -
  ACEPOY_RS01640 (ACEPOY_01640) - 359874..359963 (+) 90 Protein_325 histidine phosphatase family protein -
  ACEPOY_RS01645 (ACEPOY_01645) - 359996..360670 (+) 675 WP_001105960.1 IS6 family transposase -
  ACEPOY_RS01650 (ACEPOY_01650) - 360811..361446 (+) 636 Protein_327 aminoglycoside 6-adenylyltransferase -
  ACEPOY_RS01655 (ACEPOY_01655) sat4 361443..361985 (+) 543 WP_000627290.1 streptothricin N-acetyltransferase Sat4 -
  ACEPOY_RS01660 (ACEPOY_01660) aph(3')-IIIa 362078..362872 (+) 795 WP_001096887.1 aminoglycoside O-phosphotransferase APH(3')-IIIa -
  ACEPOY_RS01665 (ACEPOY_01665) - 363148..363279 (+) 132 Protein_330 HTH domain-containing protein -
  ACEPOY_RS01670 (ACEPOY_01670) - 363355..364100 (+) 746 Protein_331 helix-turn-helix transcriptional regulator -
  ACEPOY_RS01675 (ACEPOY_01675) - 364211..364870 (+) 660 WP_000802831.1 dihydrofolate reductase family protein -
  ACEPOY_RS01680 (ACEPOY_01680) - 365378..366052 (-) 675 WP_001105960.1 IS6 family transposase -
  ACEPOY_RS01685 (ACEPOY_01685) - 366097..366285 (-) 189 Protein_334 undecaprenyl-diphosphate phosphatase -
  ACEPOY_RS01690 (ACEPOY_01690) - 366299..367036 (-) 738 WP_000369394.1 ABC transporter permease -
  ACEPOY_RS01695 (ACEPOY_01695) - 367029..367958 (-) 930 WP_000793446.1 ABC transporter ATP-binding protein -
  ACEPOY_RS01700 (ACEPOY_01700) - 368074..368955 (-) 882 Protein_337 sensor histidine kinase -
  ACEPOY_RS01705 (ACEPOY_01705) braR 368952..369626 (-) 675 WP_000866106.1 response regulator transcription factor Regulator
  ACEPOY_RS01710 (ACEPOY_01710) - 369766..370440 (-) 675 WP_001105960.1 IS6 family transposase -
  ACEPOY_RS01715 (ACEPOY_01715) mobV 370470..371669 (-) 1200 WP_001829561.1 MobV family relaxase -
  ACEPOY_RS01720 (ACEPOY_01720) tet(K) 371858..373237 (-) 1380 WP_000492283.1 tetracycline efflux MFS transporter Tet(K) -
  ACEPOY_RS01725 (ACEPOY_01725) - 373434..374108 (+) 675 WP_001105960.1 IS6 family transposase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25839.93 Da        Isoelectric Point: 4.9884

>NTDB_id=1044064 ACEPOY_RS01705 WP_000866106.1 368952..369626(-) (braR) [Staphylococcus aureus strain P3L30A]
MKVLIVEDDLVIGKMLAEELKKWQLEPILIEGFNHVMDAFNTNAPELVLLDINLPAFNGYHWCQEIRKVSTVPIIFISSR
NDSMDQVMAMQMGADDFIEKPFNMTVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAAKLKFNEETIDLTHTELQIMH
SLFQNKGKFVSRNALIEKCWESEHFIDDNTLAVNITRLRKKLQKLGLTDFIETKKNVGYRVGDV

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1044064 ACEPOY_RS01705 WP_000866106.1 368952..369626(-) (braR) [Staphylococcus aureus strain P3L30A]
ATGAAAGTATTAATCGTAGAGGATGACTTAGTTATCGGGAAGATGCTTGCTGAAGAGCTCAAGAAGTGGCAGCTAGAACC
GATCTTAATAGAAGGTTTCAATCATGTAATGGATGCCTTCAACACGAATGCACCGGAACTTGTGTTACTCGATATTAATT
TACCTGCCTTCAATGGTTATCACTGGTGTCAGGAGATTCGTAAAGTTTCTACTGTACCGATTATATTTATTAGTTCGCGT
AACGACAGTATGGATCAAGTAATGGCGATGCAGATGGGTGCGGATGATTTCATTGAGAAGCCATTTAATATGACTGTTAC
AATTACTAAGATTCAAGCACTATTACGCCGCACGTATGATTTCACCACTCAAGTTAATAATTTAACAGTAGATGATTGCG
AGTTACTACTTGATGCAGCAAAGCTTAAATTTAATGAAGAAACCATAGACCTGACACACACTGAATTGCAAATCATGCAT
AGCTTATTCCAGAACAAGGGCAAATTCGTCAGTCGTAATGCGTTAATCGAAAAATGCTGGGAATCAGAACACTTCATTGA
TGACAATACGCTTGCTGTCAACATTACACGTTTACGCAAAAAGCTACAAAAACTAGGACTTACAGATTTTATCGAAACGA
AGAAAAATGTCGGATATCGTGTAGGTGACGTATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

66.516

98.661

0.656

Multiple sequence alignment