Detailed information NTG1043604

Bioinformatically predicted

Overview

• Name: hexB
• Type: Machinery gene
• Locus tag: QOR62_RS10250
• Genome accession: NZ_OX460940
• Coordinates: 2024512..2026485 (-)
• Length: 657 a.a.
• NCBI ID: WP_283572331.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae isolate MRI Z2-179
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2019512..2031485

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QOR62_RS10225	recA	2019521..2020660 (-)	1140	WP_001085740.1	recombinase RecA	Machinery gene
QOR62_RS10230	cinA	2020734..2021993 (-)	1260	WP_001200975.1	competence/damage-inducible protein A	Machinery gene
QOR62_RS10235	-	2022082..2022633 (-)	552	WP_000817341.1	DNA-3-methyladenine glycosylase I	-
QOR62_RS10240	ruvA	2022656..2023246 (-)	591	WP_000272490.1	Holliday junction branch migration protein RuvA	Machinery gene
QOR62_RS10245	-	2023248..2024480 (-)	1233	WP_000657472.1	MFS transporter	-
QOR62_RS10250	hexB	2024512..2026485 (-)	1974	WP_283572331.1	DNA mismatch repair endonuclease MutL	Machinery gene
QOR62_RS10255	-	2026711..2026914 (+)	204	WP_000191849.1	cold shock domain-containing protein	-
QOR62_RS10260	hexA	2026971..2029547 (-)	2577	WP_001118379.1	DNA mismatch repair protein MutS	Machinery gene
QOR62_RS10265	argR	2029604..2030041 (-)	438	WP_001033152.1	arginine repressor	-

Sequence

Protein

• Length: 657 a.a.
• Molecular weight: 73819.88 Da
• Isoelectric Point: 5.2043

>NTDB_id=1043604 QOR62_RS10250 WP_283572331.1 2024512..2026485(-) (hexB) [Streptococcus agalactiae isolate MRI Z2-179]
MSKIIELPDILANQIAAGEVVERPSSVVKELVENAIDAGSSQITIEVEESGLKKIQITDNGEGMTSEDAVLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASISLMTIKTATEQGKQGTLLVAKGGNIEKQEVVSSPRGTKILVENLFFNTPARLKY
MKSLQSELAHIIDIVNRLSLAHPEVAFTLINDGKEMTKTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEISGYVSLP
ELTRANRNYITLLINGRYIKNFLLNRSILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKERELMSLISS
AISESLKQYDLIPDALENLAKTSTRSVDEPIQTSFSLKQPGLYYDRTKNDFFIDADTVSEPIANFTNLDKSDGSVDNDVK
NSVNQGATQSPNIKYASRDQADSENFIHSQDYLSSKQSLNKLVEKLDSEESSTFPELEFFGQMHGTYLFAQGNGGLYIID
QHAAQERVKYEYYREKIGEVDNSLQQLLVPFLFEFSSSDFLQLQEKMSLLQDVGIFLEPYGNNTFILREHPIWMKEEEVE
SGVYEMCDMLLLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARHLLDQLAQCKNPYNCPHGRPVLVNFTKADMEKM
FKRIQENHTSLRDLGKY

Nucleotide

• Length: 1974 bp

>NTDB_id=1043604 QOR62_RS10250 WP_283572331.1 2024512..2026485(-) (hexB) [Streptococcus agalactiae isolate MRI Z2-179]
TTGTCTAAAATTATTGAATTACCGGATATATTAGCTAACCAGATTGCTGCTGGTGAGGTTGTTGAAAGACCTAGTAGCGT
CGTTAAAGAATTAGTTGAAAATGCCATAGATGCAGGAAGTAGCCAAATTACCATAGAGGTTGAAGAATCTGGTCTTAAAA
AGATTCAAATAACGGATAACGGTGAAGGGATGACTAGTGAGGATGCTGTTCTCAGTTTACGACGTCACGCTACATCCAAA
ATCAAAAGCCAGAGTGACCTTTTTCGTATTCGGACCTTAGGTTTTCGTGGTGAAGCCCTACCATCAATCGCTTCGATTAG
TTTAATGACGATAAAAACAGCTACAGAGCAAGGGAAACAAGGGACGTTACTTGTTGCTAAAGGGGGAAACATTGAAAAAC
AGGAAGTTGTTTCAAGTCCTCGTGGAACAAAAATTTTAGTTGAAAATTTATTCTTTAATACGCCTGCCAGATTGAAATAC
ATGAAGAGTTTACAGTCTGAACTAGCTCATATTATTGATATTGTTAATAGACTCAGTCTAGCGCATCCGGAAGTTGCTTT
TACACTGATAAATGATGGTAAAGAAATGACTAAAACTAGTGGGACTGGCGATTTGAGACAGGCGATTGCAGGTATTTATG
GTTTAAATACTGCAAAAAAAATGATTGAGATTTCAAATGCAGATTTAGATTTTGAAATTTCGGGTTATGTAAGTTTGCCT
GAATTGACACGAGCTAACCGAAACTATATTACCCTATTAATTAACGGTCGTTACATTAAAAATTTTCTTTTAAACCGCTC
AATTCTAGATGGTTATGGTTCAAAGTTGATGGTTGGAAGATTTCCAATTGCTGTCATTGATATTCAGATAGATCCTTATC
TAGCAGATGTCAACGTTCATCCGACTAAGCAAGAGGTGAGAATTTCTAAGGAACGAGAATTAATGAGTTTAATAAGCTCA
GCAATTTCTGAGAGTCTTAAACAATATGATTTGATTCCGGATGCTTTAGAGAATTTAGCTAAAACTAGTACCCGAAGTGT
AGATGAGCCTATACAAACAAGCTTCTCACTAAAACAGCCTGGTTTGTATTACGATAGGACTAAAAATGACTTTTTTATAG
ATGCAGATACTGTATCTGAACCTATTGCTAACTTTACAAACCTTGACAAAAGTGACGGTTCAGTTGACAATGATGTAAAA
AACTCTGTTAATCAAGGAGCAACGCAGTCTCCTAATATAAAGTATGCTAGTAGAGATCAAGCTGATAGTGAGAACTTCAT
TCATTCTCAGGACTACCTTAGTAGTAAACAGTCACTTAACAAACTTGTTGAAAAATTAGATTCGGAAGAAAGTTCGACTT
TTCCAGAGCTCGAATTTTTTGGTCAAATGCATGGGACCTACTTATTTGCTCAAGGGAATGGTGGGTTGTATATTATTGAT
CAACATGCAGCTCAAGAGCGTGTAAAATACGAGTATTACCGTGAAAAGATAGGTGAGGTTGATAATAGTCTTCAACAATT
GTTAGTACCATTTCTATTTGAATTTTCAAGTTCAGATTTTCTTCAATTACAAGAAAAAATGTCATTATTACAAGATGTTG
GTATTTTCTTGGAACCGTATGGTAATAATACTTTCATTTTAAGGGAACATCCAATTTGGATGAAAGAAGAAGAGGTAGAG
TCTGGCGTTTATGAAATGTGTGATATGTTGTTGCTCACTAATGAAGTCTCAGTGAAAAAATATCGCGCAGAGTTGGCTAT
TATGATGTCTTGCAAGCGATCTATTAAAGCAAACCATACGCTAGACGATTACTCAGCACGTCATTTATTAGATCAGTTAG
CGCAATGTAAAAATCCTTATAATTGCCCTCATGGAAGACCTGTTTTAGTTAATTTTACAAAAGCTGATATGGAGAAAATG
TTTAAACGAATCCAAGAAAATCATACAAGCCTCAGGGATTTAGGAAAATATTGA

Domains

Predicted by InterProScan.

• MutL C terminal dimerisation domain (MutL_C) (458-601)

• DNA mismatch repair protein, C-terminal domain (DNA_mis_repair) (209-326)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3) (25-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexB	Streptococcus pneumoniae R6	68.892	100	0.691