Detailed information NTG1043209

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACEN2Z_RS09315
• Genome accession: NZ_CP168221
• Coordinates: 1912560..1913603 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain C92
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1907560..1918603

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACEN2Z_RS09285 (ACEN2Z_09285)	-	1907982..1909238 (-)	1257	WP_001789555.1	aminopeptidase	-
ACEN2Z_RS09290 (ACEN2Z_09290)	-	1909241..1909441 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACEN2Z_RS09295 (ACEN2Z_09295)	-	1909588..1910052 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACEN2Z_RS09300 (ACEN2Z_09300)	-	1910059..1910334 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACEN2Z_RS09305 (ACEN2Z_09305)	-	1910612..1911829 (+)	1218	WP_373334080.1	YihY/virulence factor BrkB family protein	-
ACEN2Z_RS09310 (ACEN2Z_09310)	vraR	1911941..1912570 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
ACEN2Z_RS09315 (ACEN2Z_09315)	vraS	1912560..1913603 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACEN2Z_RS09320 (ACEN2Z_09320)	liaF	1913600..1914301 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACEN2Z_RS09325 (ACEN2Z_09325)	-	1914316..1914702 (-)	387	WP_001110179.1	hypothetical protein	-
ACEN2Z_RS09330 (ACEN2Z_09330)	map	1914919..1915677 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACEN2Z_RS09335 (ACEN2Z_09335)	-	1916205..1917191 (+)	987	WP_000999714.1	aromatic acid exporter family protein	-
ACEN2Z_RS09340 (ACEN2Z_09340)	-	1917623..1918036 (-)	414	WP_025173836.1	hypothetical protein	-
ACEN2Z_RS09345 (ACEN2Z_09345)	-	1918065..1918175 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1043209 ACEN2Z_RS09315 WP_001017131.1 1912560..1913603(-) (vraS) [Staphylococcus aureus strain C92]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1043209 ACEN2Z_RS09315 WP_001017131.1 1912560..1913603(-) (vraS) [Staphylococcus aureus strain C92]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1