Detailed information NTG1042807

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK28_RS14075
• Genome accession: NZ_CP168158
• Coordinates: 2789544..2790431 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CUBIST-49
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2784544..2795431

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK28_RS14045 (ACCK28_14045)	-	2784563..2784655 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK28_RS14050 (ACCK28_14050)	-	2784763..2785260 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK28_RS14055 (ACCK28_14055)	-	2785270..2785530 (-)	261	WP_001789910.1	hypothetical protein	-
ACCK28_RS14060 (ACCK28_14060)	-	2785912..2786025 (-)	114	WP_001791776.1	hypothetical protein	-
ACCK28_RS14065 (ACCK28_14065)	-	2786684..2788684 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACCK28_RS14070 (ACCK28_14070)	-	2788681..2789436 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK28_RS14075 (ACCK28_14075)	braS	2789544..2790431 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK28_RS14080 (ACCK28_14080)	braR	2790442..2791107 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK28_RS14085 (ACCK28_14085)	-	2791133..2791333 (-)	201	WP_000604728.1	hypothetical protein	-
ACCK28_RS14090 (ACCK28_14090)	-	2791531..2792955 (+)	1425	WP_000953744.1	alkaline phosphatase	-
ACCK28_RS14095 (ACCK28_14095)	-	2793015..2793116 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACCK28_RS14100 (ACCK28_14100)	-	2793238..2793693 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK28_RS14105 (ACCK28_14105)	-	2793938..2794699 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1042807 ACCK28_RS14075 WP_000143419.1 2789544..2790431(-) (braS) [Staphylococcus aureus strain CUBIST-49]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1042807 ACCK28_RS14075 WP_000143419.1 2789544..2790431(-) (braS) [Staphylococcus aureus strain CUBIST-49]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997