Detailed information NTG1042736

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACCQ20_RS04970
• Genome accession: NZ_CP168156
• Coordinates: 1013077..1014063 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain CUBIST-2
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1008077..1019063

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCQ20_RS04945 (ACCQ20_04945)	opp4B	1008291..1009253 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ACCQ20_RS04950 (ACCQ20_04950)	opp4C	1009265..1010146 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
ACCQ20_RS04955 (ACCQ20_04955)	trpS	1010188..1011177 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ACCQ20_RS04960 (ACCQ20_04960)	spxA	1011471..1011866 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ACCQ20_RS04965 (ACCQ20_04965)	mecA	1012237..1012956 (+)	720	WP_001217728.1	adaptor protein MecA	-
ACCQ20_RS04970 (ACCQ20_04970)	coiA	1013077..1014063 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ACCQ20_RS04975 (ACCQ20_04975)	pepF	1014111..1015919 (+)	1809	WP_001655747.1	oligoendopeptidase F	-
ACCQ20_RS04980 (ACCQ20_04980)	yjbH	1016379..1017185 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ACCQ20_RS04985 (ACCQ20_04985)	-	1017208..1017573 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ACCQ20_RS04990 (ACCQ20_04990)	-	1017677..1018270 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ACCQ20_RS04995 (ACCQ20_04995)	-	1018456..1018803 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1042736 ACCQ20_RS04970 WP_000959282.1 1013077..1014063(+) (coiA) [Staphylococcus aureus strain CUBIST-2]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1042736 ACCQ20_RS04970 WP_000959282.1 1013077..1014063(+) (coiA) [Staphylococcus aureus strain CUBIST-2]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976