Detailed information NTG1042721

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK24_RS14170
• Genome accession: NZ_CP168154
• Coordinates: 2804714..2805601 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain CUBIST-6
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2799714..2810601

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK24_RS14140 (ACCK24_14140)	-	2799733..2799825 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK24_RS14145 (ACCK24_14145)	-	2799933..2800430 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK24_RS14150 (ACCK24_14150)	-	2800440..2800700 (-)	261	WP_001791974.1	hypothetical protein	-
ACCK24_RS14155 (ACCK24_14155)	-	2801082..2801195 (-)	114	Protein_2748	hypothetical protein	-
ACCK24_RS14160 (ACCK24_14160)	-	2801854..2803854 (-)	2001	WP_000776750.1	ABC transporter permease	-
ACCK24_RS14165 (ACCK24_14165)	-	2803851..2804606 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK24_RS14170 (ACCK24_14170)	braS	2804714..2805601 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK24_RS14175 (ACCK24_14175)	braR	2805612..2806277 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK24_RS14180 (ACCK24_14180)	-	2806303..2806503 (-)	201	WP_000604730.1	hypothetical protein	-
ACCK24_RS14185 (ACCK24_14185)	-	2806701..2808125 (+)	1425	WP_000953755.1	alkaline phosphatase	-
ACCK24_RS14190 (ACCK24_14190)	-	2808185..2808286 (-)	102	WP_000731976.1	SE2200 family small protein	-
ACCK24_RS14195 (ACCK24_14195)	-	2808408..2808863 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK24_RS14200 (ACCK24_14200)	-	2809108..2809869 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1042721 ACCK24_RS14170 WP_000143425.1 2804714..2805601(-) (braS) [Staphylococcus aureus strain CUBIST-6]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1042721 ACCK24_RS14170 WP_000143425.1 2804714..2805601(-) (braS) [Staphylococcus aureus strain CUBIST-6]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1