Detailed information NTG1042112

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK19_RS14610
• Genome accession: NZ_CP168091
• Coordinates: 2860372..2861259 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CUBIST-16
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2855372..2866259

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK19_RS14580 (ACCK19_14580)	-	2855391..2855483 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK19_RS14585 (ACCK19_14585)	-	2855591..2856088 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK19_RS14590 (ACCK19_14590)	-	2856098..2856358 (-)	261	WP_001789910.1	hypothetical protein	-
ACCK19_RS14595 (ACCK19_14595)	-	2856740..2856853 (-)	114	WP_011447078.1	hypothetical protein	-
ACCK19_RS14600 (ACCK19_14600)	-	2857512..2859512 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACCK19_RS14605 (ACCK19_14605)	-	2859509..2860264 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK19_RS14610 (ACCK19_14610)	braS	2860372..2861259 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK19_RS14615 (ACCK19_14615)	braR	2861270..2861935 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK19_RS14620 (ACCK19_14620)	-	2861961..2862161 (-)	201	WP_000604728.1	hypothetical protein	-
ACCK19_RS14625 (ACCK19_14625)	-	2862359..2863783 (+)	1425	WP_000953744.1	alkaline phosphatase	-
ACCK19_RS14630 (ACCK19_14630)	-	2863843..2863944 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACCK19_RS14635 (ACCK19_14635)	-	2864066..2864521 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK19_RS14640 (ACCK19_14640)	-	2864766..2865527 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1042112 ACCK19_RS14610 WP_000143419.1 2860372..2861259(-) (braS) [Staphylococcus aureus strain CUBIST-16]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1042112 ACCK19_RS14610 WP_000143419.1 2860372..2861259(-) (braS) [Staphylococcus aureus strain CUBIST-16]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997