Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACCK16_RS10425 Genome accession   NZ_CP168089
Coordinates   2078186..2078902 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain CUBIST-23     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2073186..2083902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACCK16_RS10395 (ACCK16_10395) - 2073402..2074028 (+) 627 WP_000522375.1 nitroreductase family protein -
  ACCK16_RS10400 (ACCK16_10400) - 2074389..2075174 (+) 786 WP_000867944.1 carbon-nitrogen family hydrolase -
  ACCK16_RS10405 (ACCK16_10405) - 2075775..2075909 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  ACCK16_RS10410 (ACCK16_10410) agrB 2076144..2076713 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  ACCK16_RS10415 (ACCK16_10415) agrD 2076710..2076850 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACCK16_RS10420 (ACCK16_10420) agrC 2076875..2078167 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  ACCK16_RS10425 (ACCK16_10425) agrA 2078186..2078902 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACCK16_RS10430 (ACCK16_10430) - 2078974..2079081 (+) 108 WP_031785433.1 hypothetical protein -
  ACCK16_RS10435 (ACCK16_10435) - 2079271..2080230 (-) 960 WP_372487116.1 carbohydrate kinase -
  ACCK16_RS10440 (ACCK16_10440) - 2080227..2081711 (-) 1485 WP_000141419.1 sucrose-6-phosphate hydrolase -
  ACCK16_RS10445 (ACCK16_10445) - 2081860..2082810 (-) 951 WP_000790314.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1042067 ACCK16_RS10425 WP_000688492.1 2078186..2078902(+) (agrA) [Staphylococcus aureus strain CUBIST-23]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1042067 ACCK16_RS10425 WP_000688492.1 2078186..2078902(+) (agrA) [Staphylococcus aureus strain CUBIST-23]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAGGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment