Detailed information NTG1042027

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK21_RS14320
• Genome accession: NZ_CP168087
• Coordinates: 2817948..2818835 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CUBIST-25
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2812948..2823835

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK21_RS14290 (ACCK21_14290)	-	2812967..2813059 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK21_RS14295 (ACCK21_14295)	-	2813167..2813664 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK21_RS14300 (ACCK21_14300)	-	2813674..2813934 (-)	261	WP_001789910.1	hypothetical protein	-
ACCK21_RS14305 (ACCK21_14305)	-	2814316..2814429 (-)	114	WP_001791776.1	hypothetical protein	-
ACCK21_RS14310 (ACCK21_14310)	-	2815088..2817088 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACCK21_RS14315 (ACCK21_14315)	-	2817085..2817840 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK21_RS14320 (ACCK21_14320)	braS	2817948..2818835 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK21_RS14325 (ACCK21_14325)	braR	2818846..2819511 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK21_RS14330 (ACCK21_14330)	-	2819537..2819737 (-)	201	WP_000604728.1	hypothetical protein	-
ACCK21_RS14335 (ACCK21_14335)	-	2819935..2821359 (+)	1425	WP_000953744.1	alkaline phosphatase	-
ACCK21_RS14340 (ACCK21_14340)	-	2821419..2821520 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACCK21_RS14345 (ACCK21_14345)	-	2821642..2822097 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK21_RS14350 (ACCK21_14350)	-	2822342..2823103 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1042027 ACCK21_RS14320 WP_000143419.1 2817948..2818835(-) (braS) [Staphylococcus aureus strain CUBIST-25]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1042027 ACCK21_RS14320 WP_000143419.1 2817948..2818835(-) (braS) [Staphylococcus aureus strain CUBIST-25]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997