Detailed information NTG1041985

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK22_RS15230
• Genome accession: NZ_CP168085
• Coordinates: 2940661..2941548 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain CUBIST-27
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2935661..2946548

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK22_RS15200 (ACCK22_15200)	-	2935680..2935772 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK22_RS15205 (ACCK22_15205)	-	2935880..2936377 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK22_RS15210 (ACCK22_15210)	-	2936387..2936647 (-)	261	WP_001791974.1	hypothetical protein	-
ACCK22_RS15215 (ACCK22_15215)	-	2937029..2937142 (-)	114	Protein_2963	hypothetical protein	-
ACCK22_RS15220 (ACCK22_15220)	-	2937801..2939801 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACCK22_RS15225 (ACCK22_15225)	-	2939798..2940553 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK22_RS15230 (ACCK22_15230)	braS	2940661..2941548 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK22_RS15235 (ACCK22_15235)	braR	2941559..2942224 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK22_RS15240 (ACCK22_15240)	-	2942250..2942450 (-)	201	WP_000604730.1	hypothetical protein	-
ACCK22_RS15245 (ACCK22_15245)	-	2942648..2944072 (+)	1425	WP_000953755.1	alkaline phosphatase	-
ACCK22_RS15250 (ACCK22_15250)	-	2944132..2944233 (-)	102	WP_000731976.1	SE2200 family small protein	-
ACCK22_RS15255 (ACCK22_15255)	-	2944355..2944810 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK22_RS15260 (ACCK22_15260)	-	2945055..2945816 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1041985 ACCK22_RS15230 WP_000143425.1 2940661..2941548(-) (braS) [Staphylococcus aureus strain CUBIST-27]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1041985 ACCK22_RS15230 WP_000143425.1 2940661..2941548(-) (braS) [Staphylococcus aureus strain CUBIST-27]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1