Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACCK22_RS12020 Genome accession   NZ_CP168085
Coordinates   2309781..2310497 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain CUBIST-27     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2304781..2315497
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACCK22_RS11990 (ACCK22_11990) - 2304998..2305624 (+) 627 WP_000522381.1 nitroreductase family protein -
  ACCK22_RS11995 (ACCK22_11995) - 2305985..2306770 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  ACCK22_RS12000 (ACCK22_12000) - 2307370..2307504 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  ACCK22_RS12005 (ACCK22_12005) - 2307740..2308303 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  ACCK22_RS12010 (ACCK22_12010) agrD 2308306..2308449 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  ACCK22_RS12015 (ACCK22_12015) agrC 2308479..2309762 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  ACCK22_RS12020 (ACCK22_12020) agrA 2309781..2310497 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACCK22_RS12025 (ACCK22_12025) - 2310569..2310678 (+) 110 Protein_2339 hypothetical protein -
  ACCK22_RS12030 (ACCK22_12030) - 2310866..2311825 (-) 960 WP_001253312.1 carbohydrate kinase -
  ACCK22_RS12035 (ACCK22_12035) - 2311822..2313306 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  ACCK22_RS12040 (ACCK22_12040) - 2313455..2314405 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1041981 ACCK22_RS12020 WP_000688492.1 2309781..2310497(+) (agrA) [Staphylococcus aureus strain CUBIST-27]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1041981 ACCK22_RS12020 WP_000688492.1 2309781..2310497(+) (agrA) [Staphylococcus aureus strain CUBIST-27]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment