Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ACDZ80_RS16525 Genome accession   NZ_CP168027
Coordinates   3272373..3273017 (-) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain CM35 isolate     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3267373..3278017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACDZ80_RS16490 (ACDZ80_16490) - 3268558..3268989 (+) 432 WP_007408670.1 Na(+)/H(+) antiporter subunit B -
  ACDZ80_RS16495 (ACDZ80_16495) - 3268989..3269330 (+) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  ACDZ80_RS16500 (ACDZ80_16500) - 3269323..3270804 (+) 1482 WP_053574131.1 Na+/H+ antiporter subunit D -
  ACDZ80_RS16505 (ACDZ80_16505) - 3270810..3271286 (+) 477 WP_007613428.1 Na+/H+ antiporter subunit E -
  ACDZ80_RS16510 (ACDZ80_16510) - 3271286..3271570 (+) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  ACDZ80_RS16515 (ACDZ80_16515) mnhG 3271554..3271928 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  ACDZ80_RS16520 (ACDZ80_16520) - 3271968..3272351 (-) 384 WP_053574130.1 hotdog fold thioesterase -
  ACDZ80_RS16525 (ACDZ80_16525) comA 3272373..3273017 (-) 645 WP_003152052.1 response regulator transcription factor Regulator
  ACDZ80_RS16530 (ACDZ80_16530) comP 3273098..3275401 (-) 2304 WP_373265359.1 histidine kinase Regulator
  ACDZ80_RS16535 (ACDZ80_16535) comQ 3275554..3276540 (-) 987 WP_269195024.1 class 1 isoprenoid biosynthesis enzyme Regulator
  ACDZ80_RS16540 (ACDZ80_16540) degQ 3276671..3276811 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  ACDZ80_RS16545 (ACDZ80_16545) - 3277274..3277615 (+) 342 WP_007408677.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=1041572 ACDZ80_RS16525 WP_003152052.1 3272373..3273017(-) (comA) [Bacillus velezensis strain CM35 isolate]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1041572 ACDZ80_RS16525 WP_003152052.1 3272373..3273017(-) (comA) [Bacillus velezensis strain CM35 isolate]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGACGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGACAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864

Multiple sequence alignment